Treating Chronic Inflammatory Illness Flashcards
1
Q
What is the MoA of NSAIDs?
A
Inhibit COX
2
Q
How can steroids be classified?
A
Sex hormones or adrenal corticosteroids
3
Q
What is the MoA of steroids?
A
Intracellular receptor, heat shock protein, R+S to nucleus, receptor at promoter region of gene of interest, up or down transcription to change protein
4
Q
What are the 2 effects of steroid?
A
Anti-inflammatory and an immunosuppressant
5
Q
How can DMARs be classified?
A
Immunosuppressants or DMADr
6
Q
How do Anti-TNF work?
A
Block action of TNF therefore blocks inflammation, IV or injection,
6
Q
How do Anti-TNF work?
A
Block action of TNF therefore blocks inflammation, IV or injection,