Travel-related infections Flashcards

1
Q

Give seven important imported infections

A
Malaria
Typhoid
Dengue Fever
Schistosomiasis
Rickettsiosis
Viral haemorrhagic fevers
Zika fever
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2
Q

What vector is responsible for spreading malaria?

A

female Anopheles mosquito

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3
Q

What parasite(s) are responsible for causing malaria?

A

Plasmodium spp:

  • Plasmodium falciparum
  • Plasmodium vivax
  • Plasmodium ovale
  • Plasmodium malariae
  • Plasmodium knowlesi
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4
Q

What are the symptoms of malaria?

A
Fever 
Rigors 
Aching bones 
Abdo pain 
Headache 
Dysuria 
Frequency 
Sore throat 
Cough
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5
Q

What signs are present in malaria?

A

None to begin with

Later the patient may develop splenomegaly, hepatomegaly and mild jaundice

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6
Q

Give six potential complications of malaria

A
Cerebral malaria (encephalopathy)
Blackwater fever
Pulmonary oedema
Jaundice
Severe anaemia
Algid malaria (gram-negative septicaemia)
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7
Q

How is malaria diagnosed?

A

Thick and thin blood films and microscopy

Parasites seen inside RBCs: signet ring in shape, often stuck to inside lining of red cell

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8
Q

Give two drugs used to treat malaria

A

Quinine

Artemisinins

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9
Q

What causes typhoid fever?

A

Infection of the bloodstream with salmonella typhi or salmonella paratyphi

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10
Q

Describe the clinical course of typhoid fever

A

1st week: fever, headache, abdo discomfort, cough, bradycardia, neutrophilia, confusion
2nd week: fever, rose spots, diarrhoea, tachycardia, neutropenia
3rd week: complications
4th week: recovery

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11
Q

Describe the classic presentation of dengue

A
Sudden fever
Headache/retro-orbital pain
Myalgia/arthralgia
Macular/maculopapular rash
Haemorrhagic signs
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12
Q

Give two potential complications of dengue fever

A

Dengue haemorrhagic fever

Dengue shock syndrome

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13
Q

Give three organisms that can cause schistosomiasis

A

Parasitic flatworms:
Schistosoma haematobium
Schistosoma mansoni
Schistosoma japonicum

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14
Q

List the clinical stages of schistosomiasis

A
Swimmers itch
Invasive stage
Katayama fever
Acute disease
Chronic disease (can cause neurological symptoms)
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15
Q

How is schistosomiasis diagnosed?

A

Clinical diagnosis
Antibody tests
Ova in stools and urine
Rectal snip

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16
Q

What drug is used to treat schistosomiasis?

A

Praziquantel

prednisolone if severe

17
Q

Give four infections that can cause viral haemorrhagiv fever

A

Ebola
Congo-crimea haemorrhagic fever
Lassa fever
Marburg disease