transport in mammals Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

what type is the mammalian circulatory system

A

A closed double circulation consisting of a heart, blood vessels and blood.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

inner layer of blood vessels

A

tunica intima made up of squamous epithelium cells, vary smooth to minimise friction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

middle layer of blood vessels

A

tunica media, contains smooth muscle, collagen and elastic fibre

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

outer layer of blood vessels

A

tunica externa, contains elastic fibres and collagen fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

function of arteries

A

To transport blood from the heart to living tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

structure of artery

A

small lumen, thick walls especially tunica media

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

why are the artery walls thick

A

blood is at high pressure, so the arteries need to be strong with thick walls. There are lots of elastic fibres in the tunica media which allows the walls to stretch as pulses of blood surge through at high pressure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why is their lots of elastic fibre in the artery walls

A

So that they don’t burst. So that the artery walls can stretch as high pressured blood surges through, making the artery wider and reducing the pressure. It recoils when low pressure blood goes through so that the artery becomes narrower and the pressure increases. This evens out the flow of blood.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

function of capillaries

A

To take blood as close as possible to the cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a capillary bed

A

A network of capillary’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How are capillary’s adapted for their role

A

Small so can get as close as possible to the cells, the walls are one cell thick so the oxygen doesn’t have to diffuse far.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

pressure of blood in capillary’s

A

low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

structure of capillary’s

A

the walls are made up of a single layer of endothelial cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

function of veins

A

to return blood to the heart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

thickness of vein walls

A

thin as the blood pressure is low, they have the same three layers as arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

in veins how is blood returned to the heart

A

When you tense your muscles, they squeeze on the veins in your leg raising the pressure. To keep the blood flowing in the right direction, the semilunar valves allow the blood to move towards the heart but not away from it.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Where is blood normally taken from

A

veins as they have low pressure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is blood composed of?

A

cells floating in plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is blood plasma composed of

A

water with a variety of substances dissolved into it. Solutes include plasma proteins, glucose and urea.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is tissue fluid?

A

As blood flows through capillaries, some plasma leaks out through the gaps between the cells in the walls of the capillary, into the spaces between the cells of the tissue. Identical to blood plasma but has fewer protein molecules as they cant get through the gaps in the capillary walls, thought white blood cells can

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

how does tissue fluid leave and enter the capillary

A

It leaves the capillary due too blood pressure and enters it again due to osmosis as the blood contains more protein molecules. More fluid moves out of the capillary then back in

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is tissue fluid used for

A

Surrounds each cells, exchange of materials occurs between the cells and the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what is lymph

A

The tissue fluid which is not returned to the capillary’s, and is returned to the blood system via the lymph vessels or lymphatics. Virtually identical to tissue fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Structure of lymphatics

A

Are tiny bind ending vessels, they have valves which allow tissue fluid to flow in but stops it from leaking out. The valves are wide enough to let protein molecules pass through which is important as they are too big to get into blood capillary’s, if the protein was not taken away you would die in 24 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Composition of lymph in different parts of the body

A

Near the liver it has a high concentration of proteins, a high concentration of lipids in the wall of the small intestine after a meal.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

How is lymph moved

A

by contraction of muscles around the vessels, they have smooth muscle in their walls which can contract to move it on. Has valves so moves in the right direction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Where is lymph returned to the veins

A

Lymphatics join to form lymph vessels which transports lymph to the subclavian veins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Red blood cells are shaped like biconcave discs

A

This increases the surface area to volume ratio, so oxygen can diffuse quickly in and out of the cell.

29
Q

Red blood cells are very small

A

The smalls size means that no haemoglobin molecule is far from the cell surface membrane, so the haemoglobin molecule can therefore quickly exchange oxygen with the fluid outside the cell. It also means that capillary’s can be small so the oxygen is bought as close as possible to the cell.

30
Q

Red blood cells are very flexible

A

Some capillary’s are narrower then red blood cells, so the red blood cells can deform to fit through

31
Q

Red blood cells have no nucleus, mitochondria or endoplasmic reticulum

A

So more space for haemoglobin, so maximises the amount of oxygen in the red blood cell

32
Q

Difference between white and red blood cells

A

White blood cells have a nucleus, most white blood cells are larger though lymphocytes can be smaller, white blood are spherical or irregular in shape.

33
Q

Phagocytes

A

Destroy invading microorganism by phagocytosis. Neutrophils have a lobed nuclei and granular cytoplasm. Monocyte are another type of phagocytes

34
Q

Lymphocytes

A

Destroy microorganisms by secreting antibodies. Lymphocytes are smaller then most phagocytes and have a large round nucleus with only a small amount of cytoplasm.

35
Q

Haemoglobin

A

Transports oxygen around the body, each haemoglobin molecule is made of 4 polypeptides each containing one haem group which combines with one oxygen molecule.

36
Q

what is a haemoglobin disassociation curve

A

A graph with saturation of haemoglobin with oxygen on the y-axis and partial pressure on the x-axis.

37
Q

what is partial pressure

A

The pressure exerted by an individual gas in a mixture. The total pressure of a mixture of gases is the sum of the partial pressures of its components.

38
Q

what is oxygen saturation

A

A measure of how much oxygen the haemoglobin is carrying as a percentage of the maximum it could carry.

39
Q

how does partial pressure affect saturation

A

At low partial pressure the percentage saturation of haemoglobin is low

40
Q

Why is the disassociation curve S-shaped

A

It is difficult for the first oxygen to bind to a haem group. When one oxygen molecule binds, the shape of the haemoglobin molecule is altered making it easier for the next oxygen molecule to bind making it easier for the next oxygen molecule to bind and so on. The graph plateaus as the majority of the binding sites are occupied, so it is less likely for an oxygen molecule to find an empty binding site.

41
Q

Summary of s-shape in disassociation curve

A

Once the first oxygen molecule is combined to haemoglobin a small change in partial pressure of the oxygen causes a large change in the amount of oxygen carried by haemoglobin.

42
Q

what is saturation of haemoglobin with oxygen affected by

A

partial pressure of oxygen

partial pressure of carbon dioxide

43
Q

Bohr shift equations

A

CO2 diffuses from the respiring cells into the blood plasma and into the red blood cells. In the cytoplasm of red blood cells the enzyme carbonic anhydrase turns CO2 and water into carbonic acid (H2CO3). This dissociates into hydrogen ions (H+) and hydrogen carbonate ions (HCO3-)

44
Q

Bohr shift (excluding equations)

A

Haemoglobin has a higher affinity for hydrogen ions then oxygen. So the haemoglobin bonds with the hydrogen and releases the oxygen.There is a change in the tertiary structure of the oxyhaemoglobin which causes the oxygen to be released. Haemoglobonic acid forms as the H+ binds.

45
Q

Bohr shift summary

A

The higher the partial pressure of CO2 means that oxyhaemoglobin releases oxygen more readily. For a disassociation curve the higher the pressure of CO2 means that it will be more on the right.

46
Q

Method in which most carbon dioxide is transported

A

Method described in the Bohr shift. The hydrogen carbonate ions formed are initially found in the cytoplasm but then diffuses out of the red blood cell and into the blood plasma.

47
Q

Method in which the least amount of CO2 is transported

A

Dissolves into the blood plasma

48
Q

Middle method in which CO2 is transported

A

CO2 combines with the terminal amine group of the haemoglobin molecules. This forms carbaminohaemoglobin

49
Q

Significance of Bohr shift

A

High concentration of CO2 are found in actively respiring cells which need oxygen, these high carbon dioxide concentrations cause the haemoglobin to release its oxygen more rapidly.

50
Q

How does the body accumulate to high altitudes

A

The number of red blood cells increase. They normally make up 40-50% of the blood after a few months its 50-70%. More oxygen is transported.

51
Q

Dangers at high altitude

A

Arterioles in the brain dilate, increasing the amount of blood flowing in the capilarys, fluid begins to leak from the capillary into the brain tissue. This can cause disorientation. Fluid may leak into the lungs stopping them from working.

52
Q

altitude sickness

A

An increase in breathing rate and a feeling of dizziness

53
Q

the largest artery

A

aorta

54
Q

blood vessel which goes to the lungs

A

pulmonary artery

55
Q

blood vessel going from head to heart

A

superior vena cave

56
Q

blood vessel going from rest of the body to heart

A

inferior vena cave

57
Q

blood vessel bringing blood from lungs to heart

A

pulmonary vein

58
Q

What oxygenates the heart

A

coronary arteries

59
Q

how is the left side of the heart separated from the right side

A

The septum

60
Q

where does the blood first go into in the heart

A

atrium

61
Q

What are the lower chambers of the heart called

A

ventricles

62
Q

the valves between the atria and ventricles

A

atrioventricular valves

63
Q

left atrioventricular valve

A

bicuspid valve

64
Q

right atrioventricular valve

A

tricuspid valve

65
Q

atrial systole

A

Both atria contract. Blood flows from the atria into the ventricles. Backflow of blood into the veins is stopped by closure of valves in the veins.

66
Q

Ventricular systole

A

Both ventricles contract. The atrioventricular valves are pushed shut by the pressurised blood in the ventricles. The semilunar valves in the aorta and pulmonary artery are pushed open. Blood flows from the ventricles into the arteries

67
Q

ventricular diastole

A

Atria and ventricles relax. The semilunar valves in the aorta and pulmonary artery are pushed shut. Blood flows from the veins through the atria and into the ventricles.

68
Q

walls of the different heart chambers

A

The walls of the ventricles are much thicker then the walls of the atria, because the ventricles need to develop more force when they contract, as in the left ventricle the blood needs to go around the whole body. For the right ventricle the force generated needs to be relatively small because the blood is only going to the lungs which aren’t very far away. If to high a pressure as developed, tissue fluid would accumulate in the lungs hampering gas exchange. In the atria he blood is only going to the ventricles.

69
Q

How is heart action initiated and controlled

A

SAN sends out wave of excitation, this spreads across the atria. The atria contract and non-conducting tissue prevents it from reaching the ventricles. AVN sends out wave of excitation to the ventricles, the time delay make sure that the atria and ventricles do not contract at the same time. The delay is 0.1-0.2 seconds. Purkyne tissue conducts excitation to the base of the septum. This spreads upwards in the ventricle walls, so ventricles force blood up from the base.