Nuclei Acid And Protein Synthesis Flashcards
DNA nucleotides
Deoxyribose (a pentose sugar)
A phosphate group
A nitrogenous base (adenine, cytosine, guanine or thymine)
RNA nucleotides
Ribose (a pentose sugar)
A phosphate group
A nitrogenous base (uracil, adenine, cytosine and guanine)
ATP structure
Ribose bonded with adenine and three phosphate groups
Differences between RNA and DNA
RNA has ribose, DNA has deoxyribose as it’s pentose sugar.
DNA molecules are made of two polynucleotide chains, RNA is made of one
RNA has uracil as a nitrogenous base DNA has thymine
Purines
Have a double ring structure
Adenine, guanine
Pyrimidine
Have a single ring structure
Thymine, uracil and cytosine
Complementary base pairing
Adenine always pairs with thymine and cytosine always pairs with guanine
DNA molecule structure
Two polynucleotide strands running anti parallel to each other. The strands are held together by hydrogen bonds between the bases. It is in a double helix. The phosphate and sugar groups are held together by covalent bonds
Antiparallel
The strands running in opposite directions to each other.
What carbon groups are linked to each other
The covalent sugar phosphate bond links the 5- carbon of one sugar molecule and the 3 carbon of the next. The polynucleotide strand is said to have 3’ and 5’ ends.
Polynucleotide
Many nucleotides are linked together in a long chain. This takes place in the nucleus during interphase
RNA structure
A single strand of polynucleotides
DNA replication
- The double helix unwinds and the hydrogen bonds between the bases break by DNA helicase.
- In the nucleus there are nucleotides and two extra phosphates are added, this activated the nucleotide.
- Each of the bases of the activated nucleotide pairs up with its complimentary base on the old DNA strand. DNA polymerase links the sugar and phosphate groups together. The two extra phosphates are broken off and released into the nucleus
Semi conservative
Each new molecule contains one old strand and one new strand.
Gene
A sequence of nucleotides that’s forms part of a DNA molecule which codes for a polypeptide