Transport In Animals Flashcards

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1
Q

3 factors influencing need for transport system

A

Size
SA/V Ratio
Level of metabolic activity

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2
Q

Why do multicellular organisms such as mammals require a transport system?

A

they are large
Therefore
They have a small SA/V, so the body surface is not large enough to supply all innermost cells with nutrients & remove waste via diffusion alone

Also they are endotherms; maintain their own body temp so highly metabolically active

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3
Q

Single vs double circulatory system

A

Single: blood flows through heart once for each circuit of the body

Double: blood flows through heart twice for each circuit of the body

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4
Q

5 Features of an efficient transport system?

A
  1. Fluid/medium to carry dissolved nutrients & waste
  2. A pump to create pressure to push the fluid around the body
  3. Exchange surfaces to allow substances to enter and leave the fluid

To make it more efficient:

  1. Tubes to carry the fluid by mass flow
  2. Two circuits; one to pick up oxygen & one to deliver it to the tissues
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5
Q

Why is double circulation better than single

A

In single, Blood pressure drops towards the body
So slower

Rate of exchange is slower

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6
Q

Explain the difference in pressures of systemic circulation & pulmonary circulation

A

Pulmonary is low pressure as doesnt need to travel very far and cant damage the delicate capillaries in lungs

Systemic is higher as needs to travel around the whole body; left ventricle walls are thicker than right ventricles

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7
Q

Why are atrial walls much thinner than ventricle walls

A

Only need to pump blood to the chamber below, whereas the right ventricle needs to pump blood to lungs, and left ventricle needs to pump blood around whole body

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8
Q

What is the septum

A

Wall of muscle separating the ventricles, ensuring oxygenated blood is on left and deoxygenated on right, otherwise they would mix & pO2 would be too low to meet demands of all cells

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9
Q

What is a heart attack and how does it occur?

A

When the heart is starved of oxygen and nutrients; due to a blockage in coronary arteries supplying it

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10
Q

Contrast with reasons the difference in composition of capillaries, arteries and veins

A

Lumen:
is smaller for arteries so blood is higher pressure

Endothelium: same

Elastic tissue: thicker in arteries to withstand high pressure; evens out fluctuations

Smooth muscle: thicker in arteries to reduce diameter of lumen

Collagen: thicker in arteries to withstand high pressure

CAPILLARIES ONLY ONE SQUAMOUS ENdothelial CELL THICK FOR SHORT DIFFUSION DISTANCE & very narrow lumen (same as RBC so that they are squeezed against the walls as they pass through, reducing oxygen diffusion distance)

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11
Q

Benefits of closed circulatory system than open

A

Closed is where blood stays inside vessels

This means higher pressure so meets demand quick enough

Removes waste quicker to prevent toxic build up

Transport doesnt depend on body movements, as it does in insects for example

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12
Q

Adaptions of capillary walls

A

Lumen as narrow as an RBC so it is squeezed against the walls as passes through; shorter diffusion distance for o2

Wall is single layer of squamous endothelium; short diffusion distance

Fenestrations in walls; leaky to allow plasma & dissolved substances to leave blood

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13
Q

Tissue fluid formation 6 marker

A

Hydrostatic pressure @ arteriole end higher than oncotic pressure so NFP (HP-OP) = positive
; fluid moves out

Hydrostatic pressure @ venule end = dropped due to fluid leaving; is now lower than OP so NFP = negative; fluid moves back in

10% enters lymphatic system

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14
Q

O2 transport (4 marks)

A

At high pO2, Hb has high affinity for O2, eg in alveolar capillaries

Once the 1st o2 binds to Hb, CONFORMATIONAL change in tertiary structure makes it easier for more to combine

At low pO2, HbO8 unloads O2 (respiring tissues) as has low affinity for O2

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15
Q

What is conformational change

A

Once 1 O2 binds to Hb, it is much easier for others - so soons the first binds at high enough pO2, saturation increases quickly

HENCE THE S SHAPED HB SATURATION CURVE

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16
Q

CO2 transport (6 marks)

A

@ high pCO2 (RESPIRING TISSUES), CO2 diffuses into RBC

CO2 combines with h2o VIA CARBONIC ANHYDRASE to form carbonic acid H2CO3

Dissociates to H+ and HCO3- ions

Hydrogencarbonate ions diffuse back plasma

Chloride shift: Cl- move in to balance charge lost

AT LUNGS: low pCO2 causes HCO3- & H+ to combine to CO2 and H2O

17
Q

What is the difference between fetal Hb and adult Hb and what effect does this have on Hb-O8 saturation curve

A

Fetal Hb has higher affinity for O2, as needs to pick up O2 in placenta

Where pO2 is low enough for adult Hb to unload O2

Curve shifted left (fully saturated at lower pO2)

18
Q

Describe structure of Hb

A

Quaternary protein: has 4 subunits

Each subunit = polypeptide chain & a haem (non-protein) group containing an Fe2+ ion; attracts & holds an O2

So each Hb can hold 4O2 (HbO8)

19
Q

Coordination of cardiac cycle (7 marks)

A
  1. Sino atrial node initiates wave of electrical excitation
  2. Wave spreads over atrial walls (muscle membranes)
  3. Causes atria to contract (atrial systole)
  4. Tissue @ base of atria is unable to conduct the wave; only route is Atrio ventricular node
  5. The wave is delayed at the node to allow time tor the ventricles to fill with blood before contraction
  6. Wave carried down specialised conducting (PURKYNE) tissue down interventricular septum
  7. Wave spreads up ventricle walls from apex (base); causing contraction upwards, pushing blood up towards arteries
20
Q

Describe an Electrocardiogram trace and what each wave means

A

Small p wave (Atrial excitation)

Then Q R S complex (excitation of ventricles

T wave (diastole)

21
Q

Outline the cardiac cycle including pressure changes

A
  1. Atrial systole: atria contract & ventricles relax
    So decreased atria volume
    Increased pressure in atria behind valve; causes valve to open & blood flows into ventricles
  2. Ventricular systole: ventricles contract & atria relax

Decreases ventricular volume
& increases pressure so atrioventricular valves close to prevent backflow
AND semilunar valves open ; blood forced out into pulmonary artery & aorta

  1. Diastole: ventricles & atria RELAXED
    So both their volumes increase & pressure drops below that in veins/arteries

higher pressure in arteries closes semilunar valves to prevent backflow
&
Higher pressure in veins cause blood flow intro atria