transport across membranes Flashcards

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1
Q

what is a common feature amongst all cell membranes of all organisms?

A

the cell membrane is the same

- includes membrane surrounding the organelles and the cell surface membrane

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2
Q

describe the structure of the cell membrane

A
  1. phospholipid bilayer
    - hydrophilic heads point towards water on either side of the membrane
    - hydrophobic tails so repel water point inwards
  2. embedded with protiens
    - channel or carrier (intrinsic or extrinsic)
  3. glycolipids, glycoprotiens, and cholesterol
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3
Q

describe the fluid mosaic model

A
  1. molecules within membrane move laterallly

2. mixture of phospholipids, glycoprotiens, protiens, and glycolipids

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4
Q

use the fluid mosic model to explain how a cell surface membrane is selectively perimable (how molecules can enter and leave the cell)

A
  1. phospholipid bilayer allows movement of small/non-polar/lipid-soluble molecules
    down a concenteration gradient
    restricts the movement of larger, polar molecules
  2. channel and carrier protiens
    -allows movement of water soluble/polar/ molecules and ions
    down a concenteration gradient by facilitated diffusion
  3. carrier proteins
    - allows movement of molecules against their concenteration gradient using ATP by active transport
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5
Q

explain how feature of the cell surface membrane allow it to adapt to its other funtions

A
  1. phospholipid bilayer- acts as a barrier between the internal and external enviroments of a cell
  2. bilayer is fluid- can bend to take up different shapes (phagocytosis)
  3. extrinsic proteins- cell recognition/ receptors/antigens
  4. cholesterol- regulates the stability/fluidity of the membrane
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6
Q

explain the role of cholesterol in cell membranes

A
  1. maintains the fluidity of the membranes by restricting lateral movement of the molecules making up the membrane
  2. binds fatty acid tails causing them to be closely packed together
  3. not present in bacterial cell membranes
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7
Q

how do molecules move across a membrane by simple diffusion and what factors affect the rate of simple diffusion?

A
  1. simple diffusion: net movement of small, non-polar molecules across a selectively permiable membrane down the concenteration gradient
  2. no ATP
  3. affected by:
    - surface area, concenteration gradient, thickness of surface (diffusion pathway)
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8
Q

how do molecules move across a membrane by facilitated diffusion and what factors affect the rate of facilitated diffusion?

A
  1. net movement of larger, polar molecules across a selectively perimable membrane, down a concenteration gradient
  2. through a channel or carrier protien
  3. no ATP
  4. affected by:
    - surface area, concenteration gradient, and the number of channel or carrier proteins
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9
Q

how do molecules move across a membrane by active transport and what factors affect the rate of active transport?

A
  1. net movement of molecules/ions against the concenteration gradient across a selectively perimable membrane
  2. using carrier protiens
  3. using energy from the hydrolysis of ATP, to change the shape of the tertiary structure and push the substance through
  4. affected by:
    - pH/temperature, speed of carrier protiens, number of carrier protiens, and rate of respiration
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10
Q

how do molecules move across a membrane by osmosis transport and what factors affect the rate of osmosis?

A
  1. net movement of water across a selectively permiable membrane down a water potential gradient
  2. passive
  3. water potential is the likelihood of water molecules diffusing out of or into a solution
  4. affected by:
    - surface area, water potential gradient, thickness of exchange surface/diffusion pathway
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11
Q

explain how glucose is absorbed by the cells lining the mammalian ileum

A
  1. Na+ actively transported out of epithelial cell into the blood, by Na+/K+ pump
  2. creating a concenteration gradient of Na+; higher outside the cell than inside
  3. Na+ and glucose move into cell by facilitated diffusion from ileum via a co-transporter protien; Na+ down conc gradient, glucose against conc gradient
  4. higher conc of glucose inside cell than in blood
  5. glucose moves out of cell by facilitated diffusion into blood through channel protien
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12
Q

how might cells be adapted for transport across membranes?

A
  1. increase SA

2. increase no. channel or carrier proteins

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13
Q

describe the function of the fatty acid tails in the cell surface membrane

A
  1. form(water) impermeable barrier to water-soluble substances / selectively permeable
  2. allows non-polar molecules to pass through;
  3. allows cell to maintain different concentrations either side
  4. makes membranes self-sealing; able to fuse with other
    membranes
  5. able to form vesicles / gives flexibility / fluidity;
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