transport across membranes Flashcards
what is a common feature amongst all cell membranes of all organisms?
the cell membrane is the same
- includes membrane surrounding the organelles and the cell surface membrane
describe the structure of the cell membrane
- phospholipid bilayer
- hydrophilic heads point towards water on either side of the membrane
- hydrophobic tails so repel water point inwards - embedded with protiens
- channel or carrier (intrinsic or extrinsic) - glycolipids, glycoprotiens, and cholesterol
describe the fluid mosaic model
- molecules within membrane move laterallly
2. mixture of phospholipids, glycoprotiens, protiens, and glycolipids
use the fluid mosic model to explain how a cell surface membrane is selectively perimable (how molecules can enter and leave the cell)
- phospholipid bilayer allows movement of small/non-polar/lipid-soluble molecules
down a concenteration gradient
restricts the movement of larger, polar molecules - channel and carrier protiens
-allows movement of water soluble/polar/ molecules and ions
down a concenteration gradient by facilitated diffusion - carrier proteins
- allows movement of molecules against their concenteration gradient using ATP by active transport
explain how feature of the cell surface membrane allow it to adapt to its other funtions
- phospholipid bilayer- acts as a barrier between the internal and external enviroments of a cell
- bilayer is fluid- can bend to take up different shapes (phagocytosis)
- extrinsic proteins- cell recognition/ receptors/antigens
- cholesterol- regulates the stability/fluidity of the membrane
explain the role of cholesterol in cell membranes
- maintains the fluidity of the membranes by restricting lateral movement of the molecules making up the membrane
- binds fatty acid tails causing them to be closely packed together
- not present in bacterial cell membranes
how do molecules move across a membrane by simple diffusion and what factors affect the rate of simple diffusion?
- simple diffusion: net movement of small, non-polar molecules across a selectively permiable membrane down the concenteration gradient
- no ATP
- affected by:
- surface area, concenteration gradient, thickness of surface (diffusion pathway)
how do molecules move across a membrane by facilitated diffusion and what factors affect the rate of facilitated diffusion?
- net movement of larger, polar molecules across a selectively perimable membrane, down a concenteration gradient
- through a channel or carrier protien
- no ATP
- affected by:
- surface area, concenteration gradient, and the number of channel or carrier proteins
how do molecules move across a membrane by active transport and what factors affect the rate of active transport?
- net movement of molecules/ions against the concenteration gradient across a selectively perimable membrane
- using carrier protiens
- using energy from the hydrolysis of ATP, to change the shape of the tertiary structure and push the substance through
- affected by:
- pH/temperature, speed of carrier protiens, number of carrier protiens, and rate of respiration
how do molecules move across a membrane by osmosis transport and what factors affect the rate of osmosis?
- net movement of water across a selectively permiable membrane down a water potential gradient
- passive
- water potential is the likelihood of water molecules diffusing out of or into a solution
- affected by:
- surface area, water potential gradient, thickness of exchange surface/diffusion pathway
explain how glucose is absorbed by the cells lining the mammalian ileum
- Na+ actively transported out of epithelial cell into the blood, by Na+/K+ pump
- creating a concenteration gradient of Na+; higher outside the cell than inside
- Na+ and glucose move into cell by facilitated diffusion from ileum via a co-transporter protien; Na+ down conc gradient, glucose against conc gradient
- higher conc of glucose inside cell than in blood
- glucose moves out of cell by facilitated diffusion into blood through channel protien
how might cells be adapted for transport across membranes?
- increase SA
2. increase no. channel or carrier proteins
describe the function of the fatty acid tails in the cell surface membrane
- form(water) impermeable barrier to water-soluble substances / selectively permeable
- allows non-polar molecules to pass through;
- allows cell to maintain different concentrations either side
- makes membranes self-sealing; able to fuse with other
membranes - able to form vesicles / gives flexibility / fluidity;