Transplant Drugs Flashcards
0
Q
Cortisol
A
Glucocorticoid; inhibits expression of inflammatory mediators
1
Q
Azathioprine
A
Purine analog; prodrug of 6-MP (mercaptopurine), blocks DNA synthesis
2
Q
Cyclosporine
A
Calcineurin inhibitor; blocks production of IL-2 and other cytokines in T-cells
3
Q
Mycophenolate mofetil
A
Prodrug; mycophenolate decreases purine synthesis in B- and T-cells
4
Q
Tacrolimus
A
Calcineurin inhibitor; inhibits IL-2 production in T-cells
5
Q
Sirolimus
A
mTOR inhibitor; blocks protein translation in T-cells
