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Pharm spring Exam 2 - MoA Only > Dopamine Drugs > Flashcards

Dopamine Drugs Flashcards

0
Q

Carbidopa

A

Inhibits peripheral L-AAD

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1
Q

L-Dopa

A

DA precursor

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2
Q

Tolcapone

A

Inhibits central and peripheral COMT

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3
Q

Entacapone

A

Inhibits peripheral COMT

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4
Q

Benztropine

A

Anticholinergic; inhibits action of interneuron on target cell

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5
Q

Amantadine

A

Increases DA release from terminals and decreases reuptake

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6
Q

Ropinerole

A

D2 receptor agonist

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7
Q

Pramipexole

A

D2 receptor agonist

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8
Q

Selegiline

A

Inhibit MAO-B from metabolizing DA in the CNS

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9
Q

Rasagiline

A

Inhibit MAO-B from metabolizing DA in the CNS

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10
Q

Chlorpromazine

A

D2 antagonist, primarily, in the phenothiazine class. Also: 5-HT1 & 2 antagonist; antihistamine; alpha 1 & 2 antagonist; M1 & 2 Ach-receptor antagonist

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11
Q

Haloperidol

A

Strong D2 antagonist, alpha 1 antagonist, 5-HT2 antagonist

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12
Q

Clozapine

A

Atypical antipsychotic; partial 5HT1a antagonist, mesolimbic-specific D2 antagonist

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13
Q

Risperidone

A

Atypical antipsychotic; D2 antagonist, 5-HT antagonist, alpha1 & 2 antagonist, antihistamine

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14
Q

Olanzapine

A

Atypical antipsychotic; 5-HT2a antagonist, D2 antagonist, alpha1 & 2 antagonist, Anti-muscarinic

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15
Q

Ziprasidone

A

Atypical antipsychotic; 5-HT antagonist, D2 antagonist, alpha1 & 2 antagonist, some antihistamine

16
Q

Aripiprazole

A

Atypical antipsychotic; Partial D2 receptor & 5-HT1a agonist

Pharm spring Exam 2 - MoA Only (5 decks)

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