Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

ANGELO FLASHCARDS > TRANSFUSION PRACTICES > Flashcards

TRANSFUSION PRACTICES Flashcards

1
Q

Procedure whereby wholee blood is separated by physical means into componeents and one or more of them returned to the donor

A

Apheresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Blood drawn from the patient/recipient for re transfusion into him/her at later date

A

AUTOLOGUS BLOOD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

A facility or ceeeenter ttthat perfoorrms all the fooollowoing functions including:

Recruiting blooodo donors
Screening and selecting blood donors
Blood collection
Testing and prroceessing of blood units

A

Blood Center

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

A center that is involved in the following functions only:

Receiving and storing screened blood and blood components from another authorized blood establishment
Perforrrming compatibility testting
Blood issue forr transfusion

A

Blood Storage Center

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A therapeutic constituent of blood tthat is separated by physical or mechanical meeans

A

Blood Component

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

A procedure whereby a single donation blood is colleccected in a anttticoaguulant solution

A

Blood Collection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

A therapeutic substancce derived from human blood including whole blood, blood components and plasma derived products

A

Blood Productt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

To set tthe measurement of equipmeent against a known standard

A

Calibrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

System of collectting and processing blood in containers that have been connected togetheer by tthe manuufactuure before sterilization,, so that there is no possibility of bacterial or viral contamination from outside after the collection.

A

Closed System

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Specific selection process to determine the suitability of a procedure or material

A

Evaluation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

A system,, the contents of whichh are exposed to air and outside element duuring preparation and separation of components

A

Open System

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The organizational structure,, responsibilities, policies, processes, procedures and resourcces established by executive maangement to achieve quality

A

Quality sYSTEM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

To isolate nonconforming blood, component, or material

A

Quarantine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Establishing recorded evidence that proves a high degree if assurance that aspecific process wiill consistently produce an outcome meeting its predetermined specifiaction and quality attributes.

A

Validation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Evaluating the performance of a system with regards to its effectiveness based on intended use

A

Verification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Donation is considered voluntary and no remunerated if a person gives blood, plasma, orcel;lular ocmponets of his or her own free will and receives no payment for it, either in cash or kind which could be considered a substitute for money. Small tokens, refreshments are compatible with voluntary, non-remunerated donation

A

Voluntary non-remunerated donation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

under the National
Healthcare Safety Network (NHSN), what was developed with the cooperation of the AABB and the Centers of Disease Control and
Prevention (CDC) to track, to analyze, and ultimately to improve transfusion outcomes.

A

Hemovigilance Model

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Transfusion Therapy is used primarily to treat 2 conditions

A

INADEQUATE OXYGEN && Insufficient coagulation protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Transfer of blood from one person to another without exposing it to air

A

Direct (IMMEDIATE) Transfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Removal and discarding of blood rom the recipient and simultaneous replacement with the donor’s blood.

A

Exchange Transfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Transfer of blood from a donor to a flash or other container to the recipient

A

Indirect (((MEDIATE) Transfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Transfusion in which a blood is transferred form a person who has recovered from a contagious infection into the vessels of a patient suffering with the same infection and an equal amount of blood is returned from the patient to the well person.

A

Reciprocal Transfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

2 major groups of transfusion complications

A

Immediate Transfusion Reaction & Delayed Transfusion Reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

 Reaction occurring within 24 hours of
transfusion.
 Fever >1° C increase or >38° C
 Chills/rigors
 Respiratory distress—wheezing,
coughing, dyspnea, cyanosis
 Hypertension or hypotension
 Pain—abdominal, chest, flank or back,
infusion site
 Skin manifestations—urticaria, rash,
flushing, edema
 Jaundice, hemoglobinuria
 Nausea/vomiting
 Abnormal bleeding
 Oliguria/anuria

A

Immediate/Acute transfusion reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

 Reaction occurring more than 24
hours following transfusion.
 Serum hepatitis
 Syphilis
 Malaria
 AIDS/HIV

A

Delayed Transfusion Reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

2 Reactions in Delayed Transfusion Reaction

A

Immune Mediated Reaction and Non immune Mediated Reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Reaction that may be due to the component transfused, the patient’ underlying condition or the method of infusion

A

Non IMMUNE mEDIATED rEACTION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Reactions involving antigen antibody complexes, cytokine release, or complement activation

A

Immune mediated Reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Severe symptoms of an AHTR can occur after the infusion of as little as ____mL of incompatible blood

A

10 mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Most common source of HTR

A

Clerical Error

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

The destrution of transfused red cells that results in intravascular or extravascular hemolysis or a combination of both

A

Hemolyttic Transfusion Reaction

33
Q

Occur from improper handling of the donor’s blood before it is injected into the recipient’s vein.

A

Extravascular Heemolysis

34
Q

Rupture of reed cells in the circulation of the recipient

A

Intravascular Hemolysis

35
Q

ABO antibodies of the ____ class readily activate the classical pathway of complement, leading to the potential for intravascular hemolysis.

A

IgM

36
Q

Intravascular Hemolysis releases what?

A

Free Hemoglobind and Red Cell Stroma into the plasma.

37
Q

Complement functions in three capacities in an AHTR

A

Opsonization
Anaphylatoxin generation
Red Cell lysis

38
Q

Promote tissue ischemia and release of tissue factor

A

mICROVASUCLAR THROMBI

39
Q

Most prominent in an untreated AHTR

A

Renal Failure

40
Q

ERRORS KNOWN TO CAUSE AHTR

Collection of blood from the incorrect patient

A

CONTRIBUTING FACTORS CAUSING ERRORS

Insufficientsegregation of units

41
Q

ERRORS KNOWN TO CAUSE AHTR

Incorrect labeling of blood samples

A

CONTRIBUTING FACTORS CAUSING ERRORS

Preprinted sample labels

42
Q

ERRORS KNOWN TO CAUSE AHTR

Misidentification of sample at blood bank

A

CONTRIBUTING FACTORS CAUSING ERRORS

Patients with similar or identical names

43
Q

ERRORS KNOWN TO CAUSE AHTR

Issuance of wrong unit from blood bank

A

CONTRIUTING FACTORS CAUSING ERRORS

Sequential patient identifiers

44
Q

ERRORS KNOWN TO CAUSE AHTR

Alloquoting of wrong unit from blood bank

A

CONTRIBUTING FACTORS CAUSING ERRORS

Verbal and STAT orders

45
Q

In DHTR, how many hours does symptoms appear

A

24 Hours

46
Q

What Ig class causes DHTR?

A

IgG Antibody

47
Q

Newly identified red cell alloantibodies demonstrating between ____ hours and ____ days after transfusion

A

24 Hours and 28 days

48
Q

Blood group antibodies associated with delayed hemolytic reaction

(IN ORDER OF DECREASING FREQUENCY)

A

Kidd, Duffy, Kell, MNS System

49
Q

Investigation procedures in Schedule of investigation of suspectede transfusion reaction

A

Examine for visible hemolysis (a b e)
Repeat ABO (a,b,c,d)
Repeat RH (a,b,c,d)
DAT (a,b)

50
Q

Is a commonly observed adverse effect of transfusion

A

Febrile nonhemolytic transfusion reaction

51
Q

A febrile nonhemolytic reaction is typically manifested by temperature elevation of ________

A

More than 1C (or 2F)

52
Q

In patients with prior allergic reactions to tranfusion, premedication with antihistamines ______ minutes before transfusion may be beneficial.

A

30 Minutes

53
Q

How many hours after transfusion does respiratory distress and pulmonary edema occur?

A

1 — 2 hours

54
Q

Symptoms in respiratory distress and pulmonar edema

A

Hypoxemia
Tachychardia
Cyanosis
Hypotension
Fever

55
Q

In bacterial contamination of blood products, organisms are capable of grwoth at what temperature? What type of bacteri? and give examples of bacteria?

A

4 Deg C
Gram Negative Bacteria
Yersinia Enterolitica
Serratia liquefaciens
Pseudomonas fluorescens

56
Q

Gram positive organisms are more often observed in _____ stored at _______

A

20 deg C to 24 deg C

57
Q

Occurs when a patient’s cardiopulmonary system exceeds its volume capacity

A

Transfusion associated circulatory overload (TACO)

58
Q

A condition that results from the accumulation of excess iron in macrophages in various tisses

A

Hemosiderosis

59
Q

In transfusion hemosiderosis, iron intake ______ mg/unit exceeds the daily iron excretion _______ mg/day

A

250 mg/unit
1 mg/day

60
Q

What are the iron chelators will we use to prevent iron toxicity?

A

Deferiprone and Deferoxamine

61
Q

In posttransfusion purpura (PTP), the patient’s platelet count plummets how many days after the transfusion of blood or blood products containing platelents?

A

5-12 days

62
Q

A.K.A Physically or Chemically - Induced Transfusion Reactions

A

Hypothermia

63
Q

In hypothermia, the core body temperature of less that _____ usually associated with large volumes of cold fluid transfusion

A

35 Deg C

64
Q

Caused by transfusion of over ten units of stored blood causing changes in hemostatic mechanism

A

Coagulation Defects

65
Q

K and Citrate are the major source of concer

A

Biochemical Disorganization

66
Q

Diseases in delayed rtansfusion reaction

A

Serum Hepatitis (HEPA B)
Homologous Serum Jaundice
Syphylis
Malaria
AIDS/HIV

67
Q

Type of hepatitis which apparently occurs only after the transfsion of human blood or human blood products contaminated with hepatitis antigen

A

Homologous serum jaundice

68
Q

Can be transmitted in the early stage before the serologica ltests are likely to show positive result

A

Syphilis

69
Q

Malaria usually appear how many days after transfusion?

A

5 - 30 days

70
Q

The parasite in malaria may survive in what temperature

A

Refrigerated temperature

71
Q

Mean incubation period between the time fo transfusion and diagnosis of AIDS has been estimated to be how many years?

A

4-5 years

72
Q

In classic type 1 hypersensitivity, _____ antibodies in the recipient react with the allergen, which activates ______

A

IgE Antibodies
Mast Cells

73
Q

Mast cell activation results in degranulstion and the release od ____, ____, and ____.

A

Histamine
Proteases
Chemotactic Factors

74
Q

Major source of bacterial contamination of blood products

A

Improper cleansing of the donor’s skin
Transient bacteremia in an asymptomatic donor

75
Q

3 Parts of post transfusion purpura

A

Hypothermia
Coagulation Defects
Biochemical Disorganization

76
Q

Diseases in DTR

A

Serum Hepatitis
Syphilis
Malaria
AIDS/HIV

77
Q

True or False

Malaria parasites cannot survive in the body of an infected person for so many years without sign and symptoms

A

False

78
Q

Microvascular thrombi promotes what?

A

Tissue ischemia
Release of tissue factor

79
Q

ADVERSE COMPLICATION OF TRANSFUSION

Immune Mediated: Hemolytic
CAUSE in ACUTE and DELAYED

A

Acute : ABO incompatibility
Delayes : Primary/Secondary alloimunization

80
Q
A

ANGELO FLASHCARDS (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions