Transfusion Medicine Flashcards
I donated blood yesterday, but now I feel like I have the flu. What should I do?
Call the blood bank you donated to and let them know you might have a virus. They’ll autoclave and destroy it so that it doesn’t get passed on.
My blood type is A+. What antibodies do I make? If I were A- what antibodies would I make?
My blood cells only make anti-B antibodies. If I were A-, I would make anti-B and Anti-D antibodies.
Someone comes into the ER with a severe traumatic injury and has lost tons of blood. He needs blood STAT but we don’t know his blood type. What should we give him?
You should give him O negative blood. The other option would be to give O positive since he’s a male (and also not a pregnant female)
Explain the general process for a normal transfusion.
First you would want to find a donor whose blood type matches that of the recipient. You would then test their blood by mixing the two together and observing to see if it agglutinates. You would then add a Coombs reagent and look for IgG or complement.
What is the universal donor? What is the universal recipient?
Universal donor=O-
Universal acceptor=AB+
Quick review: What are the characteristics of warm?
What are the characteristics of cold? Include therapies for both.
Warm=extravascular, strong IgG, weak complement. Block the RE system.
Cold=intravascular, strong IgM, strong complement. Use immunosuppressive therapy or plasma exchange.
T or F?
While it normally lasts 35 days, you can use store whole blood for 42 days under special solutions.
False
This is true for Packed Red Blood Cells (PRBC)
What percentage is the Hct at in Whole Blood and in PRBC?
WB-36-40%
PRBC-70% (can go up to 90%)
How long does platelet and neutrophil function last in stored whole blood?
It’s all lost within 24 hours
T or F?
WNV (West Nile Virus) is the disease that has the highest risk of transfusion transmission.
True. The risk is 1:15,000
Know that the donated blood is screened for lots of infectious agents (Syphilis, Hep A B C, HIV, WNV, CMV, etc.)
For other agents associated with travel (CJD, Dengue, Malaria, etc), a history is performed on geographic exposure as well as an antibody screen done.
