Transfusion Medicine Flashcards
1
Q
What causes FNHTR
A
recipient Abs to donor leukocytes
2
Q
When does DHTR occur
A
5-14 days later
3
Q
What causes TRALI
A
donor Ab to recipient leukocytes
4
Q
Massive transfusion protocol
A
1: 1:1 with TXA and cryo prn
5
Q
Factors in cryo (4)
A
I
VWF
VIII
XIII
6
Q
SIckle cell extended antigen match
A
ABO
RhD (CcEe)
KELL (Kk)
7
Q
Minor blood group Ags
-most common to cause DHTR
A
Rh C c E e
Kell K k -
Duffy Fya Fyb
Kidd Jka Jkb - DHTR
MNS
8
Q
Alloimmunization to PLT occurs this way
A
Donor PMNs express HLA1 which leads to alloimmunization and targeting of donor PLT with HLA1 expression
