Thrombosis And hemostasis Flashcards
1
Q
Management of Lab APLS in pregnancy
A
ASA ante and postpartum
2
Q
Management of obstetrical APLS
A
- fetal loss > LMWH and ASA ante and postpartum
- growth restriction and pre eclampsia > ASA > ASA if NSVD // LMWH if CS
3
Q
Management of APLS In pregnancy
A
- LMWH and ASA > VKA
4
Q
Peripartum ppx for
- provoked VTE
- unprovoked
- OCP
A
- post only
- both
- both
5
Q
Peripartum ppx (no prior VTE)
- +/- Leiden
- CS
- AT3
- compound het or homozygous
A
- none
- post of family hx
- ante and post if family hx
- both ante and post
6
Q
Postpartum VWD care
A
- goal ACT >50 3-5 days
- TXA ppx 25mg/kg 10-14 days
7
Q
Tx for VWD minor and major bleeding
A
Minor - ddAVP or humate (goal 50)
Major - humate (goal 100, 3-5 days)
8
Q
Type 2N VWD distinguishing features
A
- NL antigen
- very low factor 8 (<1/3)
9
Q
Type 2M Vwd distinguishing features
A
- Ag/ACT <0.7
- NL multimers
10
Q
Type 2a and 2b VWD distinguishing features
A
- Ag:ACT <0.7
- multimers - low
RIPA
2a - decreased
2b - increased