Thrombosis And hemostasis Flashcards

1
Q

Management of Lab APLS in pregnancy

A

ASA ante and postpartum

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2
Q

Management of obstetrical APLS

A
  • fetal loss > LMWH and ASA ante and postpartum
  • growth restriction and pre eclampsia > ASA > ASA if NSVD // LMWH if CS
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3
Q

Management of APLS In pregnancy

A
  • LMWH and ASA > VKA
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4
Q

Peripartum ppx for
- provoked VTE
- unprovoked
- OCP

A
  • post only
  • both
  • both
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5
Q

Peripartum ppx (no prior VTE)
- +/- Leiden
- CS
- AT3
- compound het or homozygous

A
  • none
  • post of family hx
  • ante and post if family hx
  • both ante and post
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6
Q

Postpartum VWD care

A
  • goal ACT >50 3-5 days
  • TXA ppx 25mg/kg 10-14 days
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7
Q

Tx for VWD minor and major bleeding

A

Minor - ddAVP or humate (goal 50)
Major - humate (goal 100, 3-5 days)

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8
Q

Type 2N VWD distinguishing features

A
  • NL antigen
  • very low factor 8 (<1/3)
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9
Q

Type 2M Vwd distinguishing features

A
  • Ag/ACT <0.7
  • NL multimers
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10
Q

Type 2a and 2b VWD distinguishing features

A
  • Ag:ACT <0.7
  • multimers - low

RIPA
2a - decreased
2b - increased

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