Transfer Of Antibodies

Question 1

Primates, Rodents, and Humans (Hemochorial placenta)

Answer 1

Transfers IgG to placenta where mother=newborn

Question 2

Dogs and Cats (endotheliochorial placenta)

Answer 2

5-10% transferred to fetus rest is transferred through colostrum.

Question 3

Ruminants (syndesmochorial)

Answer 3

IgG transferred through colostrum only

Question 4

IgG Receptor

Answer 4

FcRn

Question 5

Location of FcRn Receptor

Answer 5

Endothelial intestinal cells

Question 6

Human and Primates Primary Igs in Milk and Colostrum

Answer 6

IgA in milk and colostrum

Question 7

Dogs Primary Igs in Milk and Colostrum

Answer 7

Milk-IgA Colostrum-IgG

Question 8

Cats primary Igs in Milk and Colostrum

Answer 8

IgG in both milk and colostrum.

Question 9

Pigs and Horses Primary Igs in Milk and Colostrum

Answer 9

Milk-IgA Colostrum-IgG

Question 10

Ruminants Primary Igs in Milk and Colostrum

Answer 10

IgG1 in both

Question 11

What is the most prominent Igs in most domestic animals?

Answer 11

IgG

Question 12

(True/False) Animals with a long gestation period have a fully formed adaptive immune system that is functional at adult levels.

Answer 12

False: Not functional at adult levels until several weeks after birth.

Question 13

What animal typically has a short gestation period?

Answer 13

Mice

Question 14

What immune organ developes first in fetal calves?

Answer 14

Thymus day-41

Question 15

What causes FPT (Failure of Passive Transfer)

Answer 15

Production failure, ingestion failure, or absorption failure.

Question 16

How to treat FPT in foals?

Answer 16

15hrs> feed additional 2-3L of colostrum, 15hrs< IV plasma infusion.