Immunity To Microbes

Question 1

What must a pathogen do to establish infection?

Answer 1

1.enter and invade host tissues 2. Evade the immunity of the host 3. Replicate

Question 2

What are the four families of PRRs?

Answer 2

Toll-like receptors, nucleotide-binding oligomerization domain-like receptors, c-type lectin channels, and rig-1-like receptors.

Question 3

How is complement activation activated?

Answer 3

Peptidoglycan’S in the cell walls of gram-positive bacteria and LPs in gram- negative bacteria, mannose on bacteria surface, and opsonization

Question 4

What are the responses to bacterial infections?

Answer 4

Neutralization of toxins, killing of bacteria, opsonization, phagocytosis, destruction,

Question 5

Where do Extra cellar bacterial infections occur?

Answer 5

Intestinal region, blood circulation,and lumen of resp, urogenital, and GI

Question 6

What does the humoral immune system do in bacterial infections?

Answer 6

IgA is directed to cell wall to neutralize toxins, opsonization is done with IgG, and classical complement by IgG and IgM

Question 7

What is the role of cell mediated response on intracellular bacterial infections?

Answer 7

Release of mhc class II by infected macrophages,and releases IFN gamma which makes pathogens more detectable