Transcription/Translation Flashcards

1
Q

Inhibits initiation of transcription
High Mucosal penetrating AB
Can use alone for N. men
Red Urine/Contacts

A

Rifampin

Rifamycin

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2
Q

30S and 50S subunits for _____

A

70S = prokaryotes

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3
Q

40S and 60S subunits for ____

A

80S = eukaryotes

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4
Q

50S Inhibitor

A

Chloramphenicol
Clarithromycin
Clindamycin (+toxin inhibitor)
Azithromycin

C3 A

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5
Q

50S Inhibitor + Toxin Inhibitor

A

Clindamycin

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6
Q

Crosses BBB, may cause aplastic anemia due to mito depression
Gram - bacteria
Rarely used

A

Chloramphenicol

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7
Q

Used in penicillin allergic patients

Most often used AB

A

Erythromycin

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8
Q

Erythromycin includes–

A

Azithromycin

Clarithomycin

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9
Q

May allow growth of C diff and then pseudomembranous enterocolitis

A

Clindamycin

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10
Q

Aminoglycosides include:

A

Gentamicin
Amikacin
Kanamycin
Tobramycin

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11
Q

Use Aminoglycosides on:

A

Gram -

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12
Q

Aminoglycosides are:
and may cause:
thus require:

A

broad spectrum
ototoxic and nephrotoxic
hospitalization

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13
Q

30S Inhibitors

A
Gentamicin
Amikacin
Kanamycin
Tobramycin
Tetracycline
Doxycycline
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14
Q

May cause upset stomach-30S inhibitor

A

Tetracycline

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15
Q

May cause dark teeth in infants, and impaired bone development, binds Ca

A

Tetracycline

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16
Q

Bacteriostatic 30S Inhibitors

A

Tetra/Doxycycline

17
Q

Topical treatment for Impetigo

Used in nose for staph/strep

A

Muprocin

18
Q

Inhibits Isoleucine tRNA

A

Muprocin

19
Q

Treats MRSA, but high resistance

A

Linezolid (oxazolidinone)

20
Q

Removes LPS from clone proteins
Binds Lipid A
Toxic

A

Polymyxin B

21
Q

Membrane disruption–MRSA

A

Daptomycin

22
Q

Block folic acid metabolism
Broad spectrum (aerobes and facultative)
Pneumo. carinii
Anaerobe resistant

A

Sulfonamides

Trimethoprim

23
Q

Antimycobacterials used for

How many?

A

TB

3