PG Synthesis Flashcards
1
Q
Blocks conversion of GA-UDP –> MA-UDP
A
Phosphonomycin
cytosol
2
Q
Blocks D-Ala D-Ala addition (di-peptide formation)
2nd line AB for TB
A
Cycloserine
Cytosol
3
Q
Blocks BPP–>BP regeneration step
Used on Grp A Strep-Topical
A
Bacitracin
Cell Membrane
4
Q
Blocks transpeptidation step by binding dipeptide
MRSA coverage
A
Vancomycin
Exterior or periplasm
5
Q
Blocks transpeptidation step
Use on Strep
A
Penicillin
Exterior or periplasm
6
Q
Don’t use on bacteria with no cell wall
Mycoplasma
A
Penicillin
7
Q
Don’t use on bacteria with non-susceptible cell wall
Mycobacterium
Chlamydia
A
Penicillin
8
Q
Block transpeptidation step, has 2 R groups
A
Cephalosporins
9
Q
PBP2a=?
A
MRSA
10
Q
Inhibits beta lactamase
A
Clavulanic Acid
11
Q
Prevents S. Aureus from using beta lactamase
Clavulanic Acid + Amoxicillin
A
Augmentin
