Lecture 6 - Antibiotics Flashcards
1
Q
Quinolone AB target:
A
DNA gyrase (topoisomerase 2 and 4)
2
Q
Risk with fluoroquinolones?
A
Enterocolitis caused by C diff
3
Q
Intercalates DNA and prevents replication
A
Metronidazole
4
Q
Inhibit initiation of transcription
A
Rifampin
Rifamycin
5
Q
Rifampin SE?
A
red urine/contacts
6
Q
Required for ribosonal binding?
A
Shine Dalgarno sequence
7
Q
Start codons:
A
AUG
GUG
8
Q
Stop codons:
A
UGA
UAG
UAA
9
Q
Bacteria have ___S ribosomes and __S and __S subunits
A
70
30S
50S
10
Q
AA removed before exotoxin release due to its inflammatory nature
A
N-formyl-Met
11
Q
Judge bacteriocidal
A
MBC
12
Q
Observe growth inhibition, done on plate
A
MIC
