Transcription Flashcards
Genetic information flows through cell
central dogma
-structurally similar
-both nucleic acid
-both are linear, unbranched, asymmetric polymers of nucleotides
RNA and DNA
DNA:
Bases
Adenine
Guanine
Cytosine
Thymine
RNA: Bases
Adenine
Guanine
Cytosine
Uracil
RNA synthesis under the direction of a DNA template
Transcription
Transcription is divided into 3 steps
Initiation
Elongation
Termination
Catalyzes the addition of complementary ribonucleotides to growing RNA chain
RNA polymerase
Specific DNA sequence at 5’ end of gene where RNA polymerase binds
Promoter
DNA sequence that is transcribed
Transcription Unit
Opposite direction
Upstream
Initiation:
Formed when RNA polymerase and associated transcription factors bind to the promoter
Transcription initiation complex
DNA strand that is copied
Template Strand