Tracts Flashcards

1
Q

Lemniscal Tract (Dorsal or Posterior Columns)

A
  • Ascending
  • Large afferent skin/muscle fibers (proprioception) + fine touch
  • Somatotopic Organization
    • Lower limbs = medial (gracile fascicle —> gracile nucleus in caudal medulla)
    • Upper limbs = lateral (cuneate fascicle —> cuneate nucleus in caudal medulla)
    • **As you move up brainstem - flips - lower limbs lateral and upper limbs medial
  • Path - dorsal root —> fascicle —> nucleus in caudal medulla —> cross over at caudal medulla (“lemniscal decussation”) —> VPL in thalamus —> somatosensory cortex (3,1,2)
  • Ipsalateral in SC - then contralateral after crossing in medulla
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Spinothalamic Tract

A
  • Ascending
  • Small afferents (pain, temp, corse touch)
  • Cross over right away in SC itself (anterolateral part of SC)
  • Somatotopic Organization
    • Lower limbs = lateral
    • Upper limbs = medial
  • Path - ascend/descend a few levels in spine via Lissauer’s tract —> synapse in gray matter (substantial gelatinous and nucleus proprius) —> cross over in SC itself —> VPL thalamus —> somatosensory (pain) and lambic system (emotion of pain)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Dorsal Spinocerebellar Tract

A
  • Ascending
  • Function = give proprioceptive info to cerebellum
  • Leg info …Clark’s nucleus (T1-L3) —> up thru posterior/lateral white matter —>thru inferior cerebellar peduncle —> cerebellum
  • Arm info…accessory cuneate nucleus (in caudal medulla)
  • CEREBELLUM = IPSALATERAL
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ventral Spinocerebellar Tract

A
  • Get integrated info from intermediate zone interneurons of thoracic and lumbar SC
    • Proprioception mixed w/ descending motor commands from pre-motor neurons
  • Cross over in SC then RECROSS b/f reaching cerebellum so… CEREBELLUM = IPSILATERAL
  • Path - axons from interneurons cross to other side in SC —> ascend ventrally near spinothalamic neurons —> join superior cerebellar peduncle
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Corticospinal Tracts (2)

A

AKA PYRAMIDAL

  • Descending
  • Voluntary movement
  • Originate in 4, 3/2/1, and 6 in cortex —> SC
  • Cross over in caudal medulla (pyramids)
  • Path - 4,6,321 in cortex —> corona radiata —> internal capsule —> cerebral peduncles —> along ventral pons —> pyramids (CROSS) —> terminated on motoneurons in SC
  • Somatotopic
    • In motor cortex - legs are medial and arms lateral
    • In internal capsule - legs posterior and arms anterior
    • In peduncles and SC - legs lateral and arms medial
  • 90% is lateral and 10% anterior (mainly axial muscles)
    • Lateral - maintains somatotopic map (lower limbs lateral/upper limbs medial); CONTRALATERAL; distal muscles
    • Anterior - ipsilateral; axial muscles
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Extrapyramidal Tracts (4)

A

ALL DESCENDING
- 1- Rubrospinal path - regulate upper body flexion muscles; not important in humans

  • 2- Vestibulospinal tract -
    • Medial - neck stability
    • Lateral - keep upright/balance by moving limbs
  • 3- Reticulospinal tract -
    • Similar function to vestibulospinal tract (posture control)
  • 4- Tectospinal tract -
    • Function = coordinated eye-head movements (move head in response to sensory input)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Brown-Dequard Syndrome

A

damage to only 1/2 SC (hemisection)

  • Ipsilateral loss of proprioception, fine discrimination and vibration (dorsal columns)
  • Contralateral loss of pain/temp/corse touch (spinothalamic)
  • Ipsilateral paralysis of distal muscles (may recover some proximal muscles b/c bilateral influence)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Anterior Cord Syndrome

A

If block anterior spinal artery…only dorsal columns spared

  • So lose pain/temp and bilateral motor control below point of lesions BUT retain fine touch and proprioception
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tabes Dorsalis

A
  • From neurosyphillis
  • infection affects dorsal columns
  • Demyelination of large afferents for proprioception …sway w/ eyes closed (Romberg test)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Afferent Fiber Classifications (4 Groups)

A

Group I or A-alpha -Large/myelinated; FASTEST; proprioception of primary muscle spindles

Group II or A-beta - Large/myelinated; SLOWER; proprioception of secondary muscle spindles; fine touch

Group III or A-gamma- Small/thinly myelinated; SLOWER; pain, temp, corse touch

Group IV or C- Small/unmyelinated; SLOWEST; pain and temp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Rubrospinal Tract

A
  • red nucleus (midbrain) —> crosses near origin (so contralateral)—> descends near lateral corticospinal tract (so posterior white matter)
  • Function = regulate voluntary upper body flexion muscles (so only goes to cervical SC)
  • Inputs from …motor and pre-motor cortex and cerebellum
  • Controls alpha and gamma of JUST UPPER LIMBS; (flexor + extensor -)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

LVST

A

-Goal= keep upright/balance by moving limbs
by EXCITING extensors and INHIBITING flexors

  • Inputs from vestibular end organs and proprioceptors in neck
  • Lateral vestibular nuclei —> shift medially (ipsilateral)—> terminate in intermediate zone
  • Commissural - influences both sides
  • Uses gamma motoneurons to enhance spindle inputs so exaggerate reflex to keep you upright; also influences alpha motoneurons
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

MVST

A
  • Medial (MVST) - neck stability so only goes to cervical SC
  • From medial vestibular nuclei then descend bilaterally
  • Input mainly to neck alpha motoneurons
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Reticulospinal Tract

A
  • From nuclei in reticular formation (diffusely organized cells)—> SC in anterior white matter
  • Medial reticular formation = motor (works indirectly on both alpha and gamma motoneurons; excites both flexors and extensors)
  • Lateral reticular formation = autonomic (BP, pattern generator for respiration, pontine micturition center)
  • Inputs from…vestibular system, somatosensory system, cortex
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tectospinal Tract

A
  • superior colliculus (crosses near origin so contralateral)—> cervical SC (only NECK alpha motoneurons) thru anterior white matter
    • Function = coordinated eye-head movements (reflective turning of head in response to visual, auditory or somatosensory info)
  • Inputs from visual, auditory, frontal eye fields
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the general trends of anteromedial motor tracts v. posterolateral motor tracts?

A
  • Posterolateral
    • Come from cortex (more feedforward control)
    • Distal muscles
    • More precise control (ex- monkeys w/ damage to corticospinal tract could not recover independent movement of ea finger)
      • Corticospinal tract is enlarged in higher animals for more precise movement
    • Monosynpatic termination on motoneurons themselves
  • Anteromedial
    • Come from brainstem (except anterior part of corticospinal tract - 10%)
    • Proximal muscles
    • Terminate on intermediate zone neurons