toxins

Question 1

neurotoxins

Answer 1

tetanus toxin

botulinum toxin

Question 2

enterotoxins

Answer 2

cholera toxin
e.coli heat labile toxin (LT) (strucutrally similar to cholera toxin)

e.coli heat stable toxin (ST)

shiga-toxin

shiga-like toxin (in e.coli)

staphylococcal heat stable toxin

heat stable toxin (b.cereus)

Question 3

Pyrogenic toxins

Answer 3

s.pyogenic toxin (SPE)

TSST-1 (s.aureus)

Question 4

Tissue invasive toxins

Answer 4

s. pyogenes:
- hemolysins/streptolysins O and S
- streptokinase
- DNAse
- Hyaluronidase
- NADase

s. aureus
- Lipase
- Penicillinase
- Straphylokinase
- Leukocidin
- Exofoliatin
- factors that bind complement

Question 5

Miscellaneous exotoxins

Answer 5

b. anthracis:
- EF
- LF
- PA

corynebacterium diphteria
- diphteria toxin

bordatella pertussis:

• pertussis toxin (AB subunit)
• adenylate cyclase
• filamentous hemagluttinin
• tracheal cytotoxin

c. difficile
- toxin A
- toxin B

pseudomonas aerginosa
- exotoxin A