Toxidromes

Question 1

Management

Answer 1

1) ABCs, ECG, pO2
2) identify toxidrome
3) antidote

Question 2

supportive care

Answer 2

intubation, IV fluids for hypotension, cardiac monitor with pO2, neuro assessment, glucose

Question 3

5 basic toxidromes

Answer 3

sympathomimetics, opiate, anitcholinergic, cholinergic, sedative hypnotics

Question 4

Sympathomimetics SX

Answer 4

hyperthermia, diaphoresis, myriasis, agitation, tachycardia, combativeness, hypertension

Question 5

Caffeine lethal dose

Answer 5

150mg/kg

Question 6

Caffeine OD

Answer 6

1) tremor, restlessness, NV, tachycardia, agitation
2) seizures, delirium, SVT, hypokalemia, hyperglycemia
3) HTN with low diastolic pressure

Question 7

sympathomimetics

Answer 7

Caffeine, Cocaine, amphetamines, ephedrine

Question 8

Opiates toxidrome

Answer 8

miosis, respiratory depression, CNS depression

Question 9

Alice in Wonderland Syndrome

Answer 9

Micropsia- everything around you is smaller than it should be

Question 10

Opioid TX

Answer 10

ventilation, Naloxone, NAC

Question 11

Anitcholinergic toxidrome

Answer 11

diminished parasympathetic activity.
Hot as Hades- fever
Mad as a hatter- delerium
Fast as a hare- tachycardia
dry as a bone- anhidrosis
red as a beet- flushing
full as a tick- urinary retention
Blind as a bat- mydriasis

Question 12

anticholinergic TX

Answer 12

bzd, physostigmine

Question 13

cholinergic toxidrome

Answer 13

increased parasympathetic activity (rest and Digest)
DUMBB BELS
Diarrhea
Urinary incontinence
Mioisis
Bradycardia
Bronchorrhea
Bronchospasm
Emesis
Lacrimation
Sweating, Salivation

Question 14

Sed-Hypnotic toxidrome

Answer 14

CNS depression, lethargy

Question 15

Serotonin Toxidrome

Answer 15

high temp, MS changes, autonomic instability, Neuromuscular abnormalites

Question 16

Serotonin drugs

Answer 16

SSRI, prozac, antidepressants, selegiline, meperidine, dextromethorphan, dextroamphetamine, ecstasy, Triptans

Question 17

Serotonin TX

Answer 17

Cyproheptadine, antipyretics, BZD

Question 18

Flu-like symptoms that can lead to meningitis

Answer 18

anthrax

Question 19

fever and leukocytosis, regional lymphadenitis, pneumonia, pharyngitis and cervical lymphadenitis

Answer 19

plague

Question 20

acute onset fever, headache, myalgia, red spots followed by rash 1-4 days later, firm deep seated vesicles or pustules

Answer 20

small pox

Question 21

diplopia, blurred vision, drooping eyelids, slurred speech, dry mouth, muscle weakness, symmetric descending paralysis

Answer 21

Botulism

Question 22

cutaneous ulcer with regional lymphadenopaty

Answer 22

Ulceroglandular tularemia

Question 23

regional lymphadenopathy with no ulcer

Answer 23

Glandular tularemia

Question 24

conjunctivitis with preauricular lymphadenopathy

Answer 24

oculoglandular tularemia

Question 25

stomatis or pharyngitis or tonsillitis and cervical lymphadenopathy

Answer 25

oropharyngeal tularemia

Question 26

pleuropulmonary disease

Answer 26

pneumonic tularemia

Question 27

flu like illness that progresses to NV

Answer 27

Viral hemorrhagic fever- Ebola, Marburg