Toxicology (W6) Flashcards
What is a toxidrome
A collection of S/S that suggest a specific poisoning
In the face of an altered LOA, what should you always assess
CBG
What pts should you specifically be cautious for child abuse when they are poisoned/OD
-pts <5 y/o or intellectually developed
-pts <1 y/o
PNS: __ & __
Rest & digest
Symptoms of a stimulated PNS
Decreased HR, conduction velocity, FOC (is mediated by the vagus nerve)
SNS: __ or __
Fight or flight
Symptoms of a stimulated SNS
Increased HR, conduction velocity, FOC (mediated by sympathetic nerves)
What are the neurotransmitters for the PNS, and SNS
PNS: acetylcholine
SNS: epinephrine and norepinephrine
What are the drug toxicologies that act on the ANS
-cholinergic drugs
-anticholinergic drugs
-adrenergic drugs
What are the 4 routes of drug absorption
Inhalation, injection, ingestion, dermal
Why is inhalation the shortest acting route of drug delivery (2-3 mins)
It provides direct access to the bloodstream via alveoli
Injection can include IV access (30-60 sec) or IM access (10-20 mins), and can cause immediate effects that impact the body how
They can be local/allergic/systemic effects
Ingestion can take from 30-90 mins, although what are some big concerns to consider
-can be absorbed into bloodstream before showing S/S
-caustic substances [alkali or acidic] can show immediate effects
The dermal/topical route can vary, from minutes to hours but what is key to remember
-can include opiates (duragesic) and organophosphates (pesticides)
-decontamination may be required
What are some terms associated with drug abuse
Drug abuse/habituation/drug addition/physical dependence/psychological dependence/tolerance/withdrawal syndrome