Toxicology

Question 1

Organophosphate antidote

Answer 1

Atropine

Pralidoxime specific to organophosphate

Question 2

Opiate antidote

Answer 2

Naloxone

Question 3

Benzodiazepine antidote

Answer 3

Flumanezil

Question 4

Paracetamol antidote

Answer 4

N-acetylcysteine

Question 5

How does N-acetylcysteine work

Answer 5

Repletes glutathione which is required to convert paracetamol into an inactive metabolite

Question 6

Complication of TCA toxicity

Answer 6

Prolonged QRS causing VT/VF

Question 7

Anticholinergic Toxicity

Answer 7

Hot as a hare, mad as a hatter, dry as a bone, blind as a bat (dilated pupils), red as a beet, the bowel and bladder lose their tone and the heart runs alone (Tachy)

Question 8

Anticholinergic Agents

Answer 8

antihistamines, antipsychotics, antidepressants, antiparkinsonians, atropine

Question 9

Cholinergic Toxicity

Answer 9

SLUDGE
Salivation, Lacrimation, Urinary Incontinence, Diarrhoea, GI cramps, Emesis
pin point pupils

Question 10

Cholinergic Agents

Answer 10

Organophosphates, carbamates

Question 11

Sympathomimetic Toxicity

Answer 11

Tachycardia, tachypnoea, hyperthermia, dilated pupils, diaphoresis

Question 12

Sympathomimetic Agents

Answer 12

Caffeine, cocaine, amphetamines/meth, Ritalin, MDMA, LSD