Toxicology Flashcards

1
Q

Approach to Poisoned Pt

A
  • ABCs
  • Charcoal
  • Gastric Lavage
  • Ionized Diuresis
  • Specific Antidotes
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2
Q

Methemoglobin (metHb) Rx

A

IV Methylene Blue

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3
Q

Heavy Metal Chelators

A
Dimercaprol
Succimer
Unithiol
Edetate Calcium Disodium
Penicillamine
Deferoxamine
Deferasirox
Prussian Blue
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4
Q

Lead Poisoning Rx

A
  • Lead Lines on the Gingivae and metaphyses of long bones
  • Acute: Tinnitus, Encephalopathy, GI
  • Chronic: Anemia, Proteinuria, Wrist drop
Rx:
Succimer (PO)
Dimercaprol
EDTA
Penicillamine
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5
Q

Arsenic Rx

A
  • In pesticides
  • Acute: Rice water stool, Garlic breath, seizures
  • Chronic: Stocking Glove Neuropathy, Alopecia

Rx:
Succimer
Dimercaprol
Unithiol

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6
Q

Iron Excess Rx

A
  • Necrotizing Gastroenteritis

Rx:
Deferoxamine (IV)
Deferasirox (PO)

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7
Q

Mercury Rx

A
  • Pneumonitis, Auditory and visual loss, paresthesia, ataxia

Rx:
Succimer (PO)
Dimercaprol (IM)
Unithiol

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8
Q

Copper/Wilson’s Dx Rx

A

Penicillamine

Treintene

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9
Q

Opiates Rx

A

Naloxone

- WITHDRAWAL: Clonidine, Methadone

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10
Q

Amphetamine & Cocaine Rx

A

Haloperidol
Lorazepam
- WITHDRAWAL: Bromocriptine, Amantadine

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11
Q

Barbs Rx

A

Bicarb (Alkaline the urine)

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12
Q

BZDs Rx

A

Flumazenil

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13
Q

Hallucinogens (LSD) Rx

A

Haloperidol

Diazepam

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14
Q

Malignant Hyperthermia Rx

A

Dantrolene

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15
Q

Serotonin Syndrome Rx

A

BZDs

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16
Q

Neuroleptic Malignant Syndrome Rx

A

Diphenhydramine Botulinum

Dantrolene

17
Q

PCP Rx

A

Haloperidol

Glutamate receptors prolonged depolarization

18
Q

Cannabis Rx

A

Abstinence

19
Q

Nicotine Rx

A

Fluoxetine
Wellbutrin
Varenicline (Chantix)
- WELLBUTRIN: Wellbutrin

20
Q

Caffeine Rx

A

Lower Caffeine Intake

Analgesics

21
Q

Inhalants (Glue) Rx

A

Support and Education

22
Q

Ethylene Glycol & Methanol Rx

A

Fomepizole

- Coma, blindness, Renal failure

23
Q

Cyanide Rx

A

Hydroxocobalamine
Sodium Thiolsulfate
Amyl Nitrate

24
Q

CO Rx

A

O2