Toxicology Flashcards
Approach to Poisoned Pt
- ABCs
- Charcoal
- Gastric Lavage
- Ionized Diuresis
- Specific Antidotes
Methemoglobin (metHb) Rx
IV Methylene Blue
Heavy Metal Chelators
Dimercaprol Succimer Unithiol Edetate Calcium Disodium Penicillamine Deferoxamine Deferasirox Prussian Blue
Lead Poisoning Rx
- Lead Lines on the Gingivae and metaphyses of long bones
- Acute: Tinnitus, Encephalopathy, GI
- Chronic: Anemia, Proteinuria, Wrist drop
Rx: Succimer (PO) Dimercaprol EDTA Penicillamine
Arsenic Rx
- In pesticides
- Acute: Rice water stool, Garlic breath, seizures
- Chronic: Stocking Glove Neuropathy, Alopecia
Rx:
Succimer
Dimercaprol
Unithiol
Iron Excess Rx
- Necrotizing Gastroenteritis
Rx:
Deferoxamine (IV)
Deferasirox (PO)
Mercury Rx
- Pneumonitis, Auditory and visual loss, paresthesia, ataxia
Rx:
Succimer (PO)
Dimercaprol (IM)
Unithiol
Copper/Wilson’s Dx Rx
Penicillamine
Treintene
Opiates Rx
Naloxone
- WITHDRAWAL: Clonidine, Methadone
Amphetamine & Cocaine Rx
Haloperidol
Lorazepam
- WITHDRAWAL: Bromocriptine, Amantadine
Barbs Rx
Bicarb (Alkaline the urine)
BZDs Rx
Flumazenil
Hallucinogens (LSD) Rx
Haloperidol
Diazepam
Malignant Hyperthermia Rx
Dantrolene
Serotonin Syndrome Rx
BZDs
Neuroleptic Malignant Syndrome Rx
Diphenhydramine Botulinum
Dantrolene
PCP Rx
Haloperidol
Glutamate receptors prolonged depolarization
Cannabis Rx
Abstinence
Nicotine Rx
Fluoxetine
Wellbutrin
Varenicline (Chantix)
- WELLBUTRIN: Wellbutrin
Caffeine Rx
Lower Caffeine Intake
Analgesics
Inhalants (Glue) Rx
Support and Education
Ethylene Glycol & Methanol Rx
Fomepizole
- Coma, blindness, Renal failure
Cyanide Rx
Hydroxocobalamine
Sodium Thiolsulfate
Amyl Nitrate
CO Rx
O2