Toxicology

Question 1

Strychnine toxicity can resemble what?

Answer 1

Tetanus

Question 2

Approach to poisoned patient ?
Resus RSI DEAD

Answer 2

Resus
R- risk assessment
S - supportive care and monitoring
I- investigations

D- decontamination
E - elimination
A - antidotes
D - disposition

Question 3

Drugs that prolong QT?
Anti- ABCD

If Torsades occurs - Rx?

Answer 3

Anti - arrhythmics eg amiodarone
Anti- biotics eg macrolide, fluoroquinolones
Anti- cychotics eg haloperidol olanzapine
Anti- depressants and diuretics eg SSRI TCA, thiazides
Anti- emetic eg ondansetron
Anti- fungal eg Fluconazole

Methadone
Chloroquine

Question 4

If Torsades occurs - Rx?

Answer 4

Mgso4 2g IV over 5-10mins

Question 5

Intractable seizures ?

Answer 5

TCA and INH overdose

Question 6

Tablets that are lethal with just one tablet
MISCAST

Answer 6

Methadone and opioids
Iron and insulin
Sulphonylureas
CCB clonidine
ASA
Suboxone (buprenorphine and naloxone)
TCAs

Question 7

Activated charcoal dosage ?

Answer 7

1g/kg 400-800ml H2O within 1hr

Question 8

Activated charcoal is contraindicated in ?
PHAILS

Answer 8

P- pesticides (organo)
H- hydrocarbon
A - acids/ alkali/ alcohols
I - iron
L - lithium
S- solvents

Question 9

Multidose activated charcoal dose and indication ?

Answer 9

Dose: 0.5g/kg 2hrly 3x doses

A
B
C
D
Q

Question 10

Multidose activated charcoal dose and indication ?

Answer 10

Dose: 0.5g/kg 2hrly 3x doses

A
B
C
D
Q

Question 11

Dialysable drugs?
IV STUMBLED