Enviro Flashcards
Datura stramonium (malpitte)
Datura brugmansia (moonflower)
Anticholinergic
Activated charcoal
If severe - physostigmine
Philodendron (elephant ear)
Monstera deliciosa (delicious monster)
Dieffenbachia (dumb cane)
Zantedechia (arum Lilly)
Calcium oxalate crystals and proteolytic enzymes
Nerium oleander
Presentation similar to digoxin
Contains Cardiac glycosides
Hyperkalaemia indication of severity
Digoxin-specific fab fragments
Ricinus communis (castor oil plant)
Ricin is cardio/renal/hepatotoxic
Vomiting then bloody diarrhea
Supportive Mx
Melia azedarah (syringa tree)
Yellow berries
Vomiting, respiratory distress, dilated pupils and seizures
Supportive Mx
Traditional herbs
Callilepis laureola (impila)
- liver failure
Ceroctis capensis (blister beetle)
Used for aphrodisiac and induce abortion
Renal failure/ haematuria
Urginea sanguinea (sekanama or slangkop)
Large onion like bulbous plant
Used for tiredness, erectile dysfunction, venereal disease and “cleansing”
Cardiac glycosides !
Digoxin fab fragments
Amanita phalloides ( death cap )
Similar: galerina and gyromitra
Sx 6-18hrs later
GIT then apparent recovery
Hepatic and renal failure
Mx:
1. MDAC charcoal
2. NAC
3. Pen G (receptor competitor )
4. Antidote - Silibinin
5. Dialysis or liver transplant
Psilocybe (magic mushrooms)
Contain psilocybin - LSD like toxin
Supportive Mx
Amanita muscaria (Mario brothers)
Amanita panterina
Sx after 1-3hrs
Anti-muscarinic and psychoactive Sx
If severe anticholinergic Sx - physostigmine
Clitocybe and Inocybe
Organophosphate like Sx
30 min -2hrs onset
Can use single dose atropine
Oleander
Foxglove
Lilly of the valley
Digoxin like toxicity
Bella Donna (deadly nightshade)
Brugmansia (angels trumpet)
Mandrake
Jimson weed (malpitte)
Anticholinergic toxidrome
Cat bite
Pasturella multocida
Bartonella henselae
Rx:
augmentin
Or ciprofloxacin (penicillin allergy)
Tetanus
Dog bite
Capnocytophagia caninorsus
Rhabdovirus (rabies)
Rx
Augmentin
Tetanus
Human bite
Eikenella corrodens
Mx:
Augmentin
Tetanus
Snakebites covered by PVA polyvalent antivenom
One: rinkals
Two: adders (Puff and Gaboon)
Three: mambas (Black, Green, Jamesons)
Four: Cobras (Mozambique, Snouted/Egyptian, Forest, Cape)
Monovalent antivenom snake ?
Boomslang
Snakes according to toxidrome
Cytotoxic:
- Adders
- spitting cobras (rinkhals, Mozambique)
-stilleto
Neurotoxic:
- mambas
- nonspitting cobras (black mamba and cape cobra)
Haemotoxic:
- Boomslang
Poisonous snakes without antivenom
Vine snake
Stilletto snake
Rhombic snake
Berg adder
Risk of anaphylaxis to antivenom
Subcutaneous adrenaline 0.25ml (1:1000)
Thick tail Scorpion - parabuthus spp
Neurotoxic - excitability
Bulbar paralysis
Autonomic instability
Mx: scorpion antivenom
NOT with prophylactic adrenaline due to autonomic instability
Ca for muscle crampsn
Monitor for dysrrhythmias and pancreatitis
Anaphylaxis treatment?
Adrenaline 1mg/ml 0.01mg/kg
Max 0.5ml
IMI anterolateral thigh
Every 5-15mins
+ promethazine
+ hydrocortisone
+ cimetidine
+ nebulise
Or glucagon if not responding to adrenaline