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Mental Health > Toxicology > Flashcards

Toxicology Flashcards

1
Q

Define hormesis

A

Dose response relationship to an agent
- low dose amounts have a beneficial effect
- high dose amounts can produce functional inhibition or toxicity

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2
Q

List the general presentation of toxicity in patients

A
  • variable depending on drug & dose
  • AMS
  • incomplete/misleading history
  • unexplained abnormal VS/labs
  • withdrawal will OPPOSE a toxic effect but can MIRROR other toxidromes
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3
Q

Describe the limitations of a urine drug screen

A
  • detect metabolites not the actual compound
  • false positives with some Rx/OTC drugs
  • false negatives/undetected: K2, BZD, fentanyl
  • can be fooled by water dilution, bleach, eye drops
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4
Q

Describe the treatment for opioid toxicity

A

Naloxone (antidote)

Initiate Buprenorphine if: in/post withdrawal, COWS >6

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5
Q

Describe the primary presentation of opioid toxicity

A

CNS depression, respiratory depression, miosis

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6
Q

Describe the etiology of acetaminophen toxicity

A
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7
Q

Describe the treatment for acetaminophen toxicity

A
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8
Q

Describe the presentation of benzodiazepine toxicity

A
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9
Q

Describe the treatment for benzodiazepine toxicity

A
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10
Q

Describe the presentation of alcohol toxicity

A
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11
Q

Describe the presentation & treatment of barbiturate toxicity

A

treatment: no antidote, dialyze

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12
Q

Describe the presentation of Z-drug toxicity

A
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13
Q

Describe the etiology of sympathomimetic toxicity

A
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14
Q

Describe the presentation of sympathomimetic toxicity

A
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15
Q

Describe the treatment of sympathomimetic toxicity

A
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16
Q

Describe the presentation of anticholinergic toxicity

A
17
Q

Describe the treatment for anticholinergic toxicity

A
18
Q

Describe the presentation of cholinergic toxicity

A
19
Q

What is the antidote to cholinergic toxicity

A

atropine

20
Q

Describe the presentation of serotonin syndrome

A
21
Q

What is the treatment for serotonin syndrome

A

“benzos till they smile”

22
Q

Describe the presentation of salicylate toxicity

A
23
Q

Describe the workup for salicylate toxicity

A
24
Q

Describe the treatment for salicylate toxicity

A
25
Q

Describe the presentation of TCA toxicity

A
26
Q

Describe the treatment for TCA toxicity

A
27
Q

What hallucinogens may present with toxicity

A
  • dextromethorphan
  • LSD
  • Ayahuasca

Mental Health (12 decks)

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