Tox: antidotes Flashcards

1
Q

Cholinergic poisoning

A

Atropine

ind: symptomatic bradycardia, excessive secretions

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2
Q

Black widow spider bite

A

Black widow antivenom

ind: persistent symptoms despite analgesia, pregnancy, very young/elderly

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3
Q

Hydrofluoric acid exposure

A

Calcium

Dermal application if local symptoms/burns, IV calcium if hypocalcemia or high concentration exposure.

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4
Q

Viper snake bite (rattlesnakes, copperheads, water moccasins)

A

CroFab

ind: progressive swelling, increased pain, coagulopathy, systemic symptoms

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5
Q

Cyanide poisoning

A

Hydroxocobalamin (B12) 5g IV

Alt: Nitrites (induces methemoglobinemia and may subsequently require methylene blue), sodium thiosulfate

(ind: suspicion in pt with acidosis, coma, seizures, hypoTN, ++lactate)

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6
Q

Iron overdose

A

deferoxamine

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7
Q

Digoxin toxicity

A

Digoxin specific Fab

ind: ventricular dysrhythmias, bradycardia not responsive to therapy, K>5.0 in acute ingestion, potentially massive OD

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8
Q

Benzo overdose

A

flumazenil

contraindicated if chronic use, co-ingestion of potentially seizure-inducing medication and elevated ICP

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9
Q

Ethylene glycol overdose

A

Fomepizole
Ethanol
Thiamine (B1)
Pyridoxine (B6)

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10
Q

Methanol

A

Fomepizole
Ethanol
Folate

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11
Q

CCB or BB overdose

A

Calcium gluconate/CaCl
High dose insulin and dextrose
Glucagon

(ind: symptomatic bradycardia, hypotension)

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12
Q

Methemoglobinemia

A

Methylene blue

ind: levels >30%, mental status changes, CP, SOB

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13
Q

Tylenol overdose

A

N-acetylcysteine

(ind: acute ingestion as per Rumack-Matthew nomogram, unknown time or repeated supratherapeutic ingestion, elevated ALT/AST, APAP level >10microg/mL)

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14
Q

Opioid overdose

A

naloxone

ind: respiratory depression

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15
Q

Sulfonylurea overdose

A

Octreotide

ind: recurrent hypoglycemia

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16
Q

Anticholinergic toxidrome

A

Physostigmine

rarely indicated. consider fif seizures, delirium, dysrhythmias

17
Q

Organophosphates

A

2-PAM (pralidoxime)

ind: symptomatic poisoning

18
Q

Warfarin

A

Vitamin K