Total Gene Numbers and Recently Described RNAs Flashcards

1
Q

What is the largest chromosome?

A

Chromsome 1 (also contains most no. of genes)

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2
Q

What is the smallest chromosome?

A

Y chromosome (also contains fewest no. of genes)

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3
Q

How many genes are in the chromosome 1?

A

2706 genes

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4
Q

How many genes are in the Y chromosome?

A

104 genes

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5
Q

How many protein-coding genes are found so far? RNA-coding genes but not polypeptide?

A

At least 21,598 protein – coding genes; 8,475 genes that code for RNA molecules but do not encode polypeptides.

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6
Q

These RNA genes currently include at least ___ ribosomal RNA (rRNA) and ___ transfer RNA (tRNA) genes.

A

727; 131

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7
Q

What are types of RNA have been characterized so far?

A

mRNA, rRNA, tRNA, small cytoplasmic RNA, microRNA, small nuclear RNAs

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8
Q

A number of additional RNA molecules including small cytoplasmic RNA, microRNA, and small nuclear RNAs are generally believed to be involved in the ____.

A

regulation of gene expression

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9
Q

This class of RNA include RNAs that participate in splicing & a subclass of 1173 small nucleolar RNA (snoRNA) genes. These are known to direct the formation and chemical modification of other RNAs such as precursor rRNAs.

A

snRNA

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10
Q

snRNA direct the chemical modification of other RNAs such as precursor rRNAs through?

A

methylation and pseudouridylation

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11
Q

____ are processed from the spliced - out introns of other genes rather than being transcribed from separate genes.

A

small nucleolar RNA (snoRNA)

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12
Q

This class of RNA is usually found in association w/ cytoplasmic proteins in complexes termed small cytoplasmic ribonucleoproteins (scRNPs), of w/c an example is the so - called signal recognition particle.

A

small cytoplasmic RNAs

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13
Q

Small cytoplasmic RNAs usually found in association w/ cytoplasmic proteins in complexes termed ____?

A

small cytoplasmic ribonucleoproteins (scRNPs)

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14
Q

Small cytoplasmic RNAs usually found in association w/ cytoplasmic proteins in complexes. An example of this complex is?

A

Signal recognition particle

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15
Q

This class of RNA are short single - stranded RNA molecules of 21 – 23 nucleotides that regulate the expression of other genes by binding to mRNAs particularly the 3 ′ untranslated region, or 3 ′ UTR, in humans & causing the degradation of the latter or blocking their translation into proteins.

A

MicroRNAs

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16
Q

MicroRNAs regulate the expression of other genes by binding to which domain of mRNAs?

A

3 ′ untranslated region

17
Q

MicroRNA binding to the UTR of mRNA causes?

A

degradation of mRNA and/or blocking of translation of such mRNA