Topo Inhibitors Flashcards

1
Q

Etoposide

A

Topo II inhibitor
Oral
Tox: N/V, hypotension, myelosuppression, ALOPECIA

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2
Q

Topotecan

A

Topo I inhibitor

IV

Tox: N/V, ALOPECIA, neutropenia

Approved for SCLC

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3
Q

Irinotecan

A

Prodrug, needs liver

Tox: SEVERE DIARRHEA, bone marrow suppression

First line drug for CRC

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