Topical Treatments-Buxton Flashcards

1
Q

THe skin has a surface area of (blank)

A

1.6-2m

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2
Q

Why is it awesome that the skin has such a large surface area?

A

enhances systemic treatment measures

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3
Q

How do active ingrediants penetrate the skin?

A

either via transepidermal or transfollicular pathways

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4
Q
What are these:
Powder
Paste
Shake lotion
Ointment
Hydrophilic ointment, cream or lotion
Water
A

vehicles for drug admin

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5
Q

When do you use topical meds?

A

if a patient has a skin disorder covering less than 30% of the body

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6
Q

What are the three main determinants to choose the right vehicle?

A

1) patients skin type
2) degree of acuity of the disease
3) nature of the lesions

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7
Q

If you have oily skin what should the drug medium be?

A

creams, lotions, or shake lotions

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8
Q

If you have dry skin what should the drug medium be?

A

ointments or pastes

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9
Q

Acute inflammatory processes are best treated with (blank) or (blank0

A

creams or lotions

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10
Q

If the lesions are weeping, what should you give?

A

shake lotions

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11
Q

What is the vehicle you should give for acute erythema?

A

shake lotion, lotion, cream

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12
Q

What is the vehicle you should give for vesicles?

A

shake lotion, gel, lotion

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13
Q

What is the vehicle you should give for blisters?

A

wet dressings, shake lotions

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14
Q

What is the vehicle you should give for crusts?

A

ointment

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15
Q
What are these:
Keratolytic agents
Cytotatic agents: Podophyllin, 5-fluorouracil
Retinoids
Antibiotics, antifungals, antiviral agents
Corticosteroids
Combination products
Tacrolimus, pimecrolimus
Nonsteroidal antiinflammatory agents
Sunscreens
A

topical agents

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16
Q

What are class I topical corticosteroids?

A

hydrocortisone and prednisolone

17
Q

What are class II topical corticosteroids?

A

Methylprednisolone aceponate, triamcinolone

18
Q

What are class III topical corticosteroids?

A

betamethasone 17-valerate

19
Q

What are Class IV (strongest) topical corticosteroids?

A

Clobetasol 17-propionate

20
Q

What are the side effects of topical steroids?

A
epidermis: atrophy
Hair follicles: steroid acne
Dermis: atrophy, striae
Pigementation: hypopigmentations
Vessels: erythema, telangiectases