Topic 7 - Endocrine Flashcards
Hypoglycemia - Autonomic features
- Diaphoresis
- Hunger
- Tingling in the mouth
- Tremor
- Tachycardia
- Pallor
- Palpitations
- Anxiety
Hypoglycemia - neurological features
- Lethargy, behavioural changes, headache, visual disturbance, slurred speech, dizziness, ALOC, seizures, coma
- NOTE - chronic poorly controlled diabetics may be relatively hypoglycemic despite having a BGL >4mmol/L
Hyperglycemia - DKA characteristics
- Hyperglycemia
- Ketosis
- Metabolic acidosis
Hyperglycemic hyperosmolar syndrome characteristics
- Hyperglycemia
- Hyperosmolarity
- Severe dehydration
HHS versus DKA
HHS is caused by relative insulin deficiency whereby sufficient insulin is produced to limit ketone production. It is most commonly seen in older patients with type II diabetes,
Hyper/poglycemia causes
6 I’s:
- Ignorance
- Infection
- Ischemia (cardiac)
- Infarct (cerebral)
- Intoxication
- Impantation
Hyperglycemia management
- 12-lead
- IV access
- IV fluids
- O2
If hyperkalemia is indicated by ECG consider:
- Calcium gluconate
- Sodium bicarbonate
- Salbutamol
Glucagon (pharmacology)
- Mobilizes hepatic glycogen and releases as glucose in systemic circulation
Glucagon (Indications)
- Symptomatic hypoglycemia (with inability to administer oral glucose)
Glucagon (Contraindications)
- KSAR or hyposensitivity to glucagon
Glucagon (Precautions)
- Nil
Glucagon (Side effects)
- None
Glucagon (Onset and half-life)
Onset: 4-7 minutes
Half-life: 3-5 minutes
Glucose gel (Indcations)
- Symptomatic hypoglycemia
Glucose Gel (Contraindications)
- Unconcious
- Difficulty swallowing
- Patients <2 years