Topic 7 Flashcards
Define genotype
The genetic constitution of an organism
Define phenotype
The expression of the genes and its interaction with the environment
Define homozygous
A pair of homologous chromosomes carrying the same alleles for a single gene
Define heterozygous
A pair of homologous chromosomes carrying 2 different alleles for a single gene
Define a recessive allele
An allele only expressed if no dominant allele is present
Define dominant allele
An allele that will always be expressed in the phenotype
Define codominance
Both alleles are equally dominant and expressed in the phenotype
What is it called when you have more than 2 alleles for a single gene
Multiple alleles
Define sex linkage
A gene whose locus is located on the X chromosome
Define autosomal linkage
genes that are located on the same chromosome (Not sex chromosomes)
Define epistasis
When one gene modifies or masks the expression of a different gene at a different locus
Define monohybrid in terms of a genetic cross
A genetic cross of a characteristic determined by one gene
Define dihybrid
A genetic cross of a characteristic determined by two genes
Monohybrid inheritance genetic diagram coding and example
Single letter, capital or lower case
B or b
Codominant inheritance genetic diagram coding and example
Gene^allele
I^BI^A
C^RC^W
Multiple allele inheritance genetic diagram coding and example
Gene^allele
I^BI^O
I^AI^O
Sex linkage inheritance genetic diagram coding and example
Chromosome^allele
X^RX^r
X^RY
Autosomal linkage inheritance genetic diagram coding and example
Single letter, capital or lower case
Aa Bb
Epistasis inheritance genetic diagram coding and example
Single letter, capital or lower case
Ee Bb
What test would you use to compare the goodness of fit of observed phenotypic ratios with expected ratios
Chi squared test
Why is there a difference between observed and expected phenotypes of an organism’s autosomally linked alleles?
Crossing over occured during meiosis
Made new combinations of gametes
How to decide what statistical test is to be used
First decide if continuous data (measurements) was collected or if frequencies were (how many individuals are in a category) - if the latter, it’s a Chi squared test
If continuous data, are you:
- investigating an association between two measurements (Correlation Coefficient)
- investigating a difference between 2 means (Student T test)
What is a species
One or more populations that can breed together to produce fertile offspring
What is the Hardy Weinberg principle and what is it used for
p^2 + 2pq + q^2 = 1 where p+q=1
Predicting the allele frequencies within a population
Define gene pool
All the alleles of all the genes within a population at one time
Define population
All the individuals of one species in one area at one time that can potentially interbreed
Define allele frequency
The proportion of an allele within the gene pool
In the Hardy Weinberg equation, what is p, q , p^2, 2pq, and q^2
p= frequency of the dominant allelle
q= frequency of the recessive allele
p^2 = frequency of homozygous dominant genotype
2pq= frequency of heterozygous genotype
q^2= frequency of the homozygous recessive genotype