Topic 53 Flashcards

1
Q

Chronic Gastritis (etiology)

A
  • prolonged Helicobacter pylory infections
  • alcoholism
  • hepatitis
  • endocrin diseases
  • infectious diseases
  • autoimmune diseases
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2
Q

Chronic Gastritis (symptoms)

A
  • not always painful
  • occasional epigastric pressure
  • discomfort

Accompanying symptoms:

  • loss of appetite
  • nausea
  • loss of weight
  • abdominal fullness
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3
Q

Chronic Gastritis (oral symptoms)

A

-erythematous, atrophic oral mucosa
(especially the dorsal surface of the tongue)
-atrophic dorsal lingual surface (lingua fuliginosa)
-glossopyrosis
-increased candidiasis tendency

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4
Q

Chronic Gastritis (differential diagnosis)

A
  • anaemia

- folic acid deficiency

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5
Q

Chronic Gastritis (therapy)

A
  • internal medical treatment

- local antiseptic and analgesic th. (Tantum Verde)

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6
Q

Gastroesophageal reflux disease (etiology)

A
  • Motility problems of the esophagus
  • Chronic chemical irritation
  • increased risk of dysplastic (precancerous) alterations and epithelial transformation
  • increased incidence of adenocarcinoma and epithelial cancers
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7
Q

Gastroesophageal reflux disease (symptoms)

A
Due to irritative, chemichal effects:
- The oral mucosa of the pharynx and
- the posterior lingual surface
-erythematous
-atrophic
-erosions
-rarely ulcers
-coated tongue
(yellowish-whitish)
-hairy tongue
-oropyrosis
-glossopyrosis
-permanent dental erosions
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8
Q

Gastroesophageal reflux disease (differential diagnosis)

A
  • acute atophic candidiasis
  • anemia
  • Sjögren’s sy.
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9
Q

Gastroesophageal reflux disease (therapy)

A
  • internal medical treatment
  • locally antiseptics
  • steroid treatment
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10
Q

Crohn’s disease - terminal ileitis (etiology)

A

unknown origin - presumably immunpathological disease

Pathogenesis:

  • affect the entire digestive system from the oral cavity to the rctum
  • extraintestinal, metastatic Crohn’s disease may also occur
  • primarily affects the ileum
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11
Q

Crohn’s disease - terminal ileitis (internal symptoms)

A
  • enteritis
  • diarrhea
  • constipation
  • malabsorbtion
  • anemia
  • arthralgia
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12
Q

Crohn’s disease - terminal ileitis (dermatological symptoms)

A
  • pyoderma vegetans
  • erythema nodosum (reddish nodules on the extensor side of the skin of the extremities)
  • periorificial erythema
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13
Q

Crohn’s disease - terminal ileitis (oral symptoms)

A

Pyostomatitis vegetans:
- erythematous and swollen mucosa
- ulcerated, deeply fissured alteration, becomes unevenly „lacerated” and resembles cobble-stone „appearence”:
- hyperplastic, granulomatous, necrotic tissues are easily detachable, and a bleeding area remains without any epithelial layers
- diffuse, red, indurated and granulomatous nodules
evolve on the lips (especially on the upper) and gingiva
- cheilitis granulomatosa (may be the firs sign of Crohn’s disease)
- multiplex fissures on the lips
- pareititis granulomatosa (granulomatous inflammations on the bucca)
- aphtous ulcers, most commonly on the palate
- angular cheilitis

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14
Q

Crohn’s disease - terminal ileitis (differential diagnosis)

A
  • pemphigus vegetans
  • granulomas due to candidiasis
  • Quincke’s oedema
  • granulomatous cheilitis
  • hydantoin-hyperplasia
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15
Q

Crohn’s disease - terminal ileitis (therapy)

A

Internal medical treatment

  • corticosteroids
  • sulfonamids
  • sulphasalazin
  • azathioprin (Imuran)
  • steroid gél (for the treatment of the oral mucosa)
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16
Q

Ulcerative Colitis (etiology)

A

-chronic, inflammatory disease of the colon which has an unknown etiology
-commonly accompanied by psychosomatic symptomes
Pathogenesis:
-the disease has a tendency to relapse and then alleviate again
-the disease may be accompanied by hypocromatic anemia, leucocytosis, hypoproteinaemia, increased erythrocyte sedimentation rate
-systemic complications:
*pyostomatitis vegetans
*gangraenous pyoderma

17
Q

Ulcerative Colitis (oral symptoms)

A
  • non-specific granulomatous alterations
  • bleeding, ulcerative, aphtoid and aphtous alterations
  • painful deep ulcers and characteristic,hypertrophyc tissue acccumulations make the surface of these alterations uneven and deeply fissured
  • yellowish pustules
  • desquamativ gingivitis

Accompanied symptoms on the skin:

  • nodular erythema
  • gangrenous pyoderma
  • whitish discoloration of the fingernails(frosted glass nails)
18
Q

Ulcerative Colitis (therapy)

A
  • internal medicine

- symptomatic treatment locally (susp. anesth., corticosteroid gel)

19
Q

Celiac disease-enteropathy caused by sensitivity to gluten (etiology)

A
  • genetical faktors
  • gluten toxicity
  • intestinal peptid deficiency
  • immune response

Pathogenesis:

  • usually begins in childhood
  • symptoms may persist in adulthood as well
  • pathological function, malabsorbtion and motility disorders of the small intestine cause:
  • GI protein loss
  • vitamin deficiencies
  • malabsorption of lipids, carbohydrates, water and iron
20
Q

Celiac disease-enteropathy caused by sensitivity to gluten (symptoms)

A
  • anemia (usually microcytic hypocromatic)
  • anorexia
  • sore bones
  • eczema of the skin
  • bleeding tendency
  • finger clubbing
21
Q

Celiac disease-enteropathy caused by sensitivity to gluten (oral symptoms)

A
  • aphtous ulcers (iron and folic acid deficiency) (small aphtae)
  • tongue: erythematous, atrophic, burning, painful
  • angular cheilitis
  • in childhood: dental hypoplasia
22
Q

Celiac disease-enteropathy caused by sensitivity to gluten (differential diagnosis)

A
  • anemia

- vitamin deficiencies

23
Q

Celiac disease-enteropathy caused by sensitivity to gluten (therapy)

A
  • primarily internal medical treatment
  • gluten-free diet
  • combined vitamin substitution
  • local antiseptic treatment
24
Q

Hepatitis (etiology)

A
  • viral infections
  • toxic liver damage
  • obstruction of biliary pathways - obstructiv jaundice (caused by malignancies or stones)

Details of Pathogenesis:

  • vitamin K malabsorption
  • hemophylia (purpuras on the face)
  • haemorrhage tendencies
  • impaired drug metabolism
25
Q

Hepatitis (symptoms)

A
  • jaundice (commonly the first symptome)
  • discoloration not associated to melanin
  • caused by bilirubin deposited from the circulation into the sclera and skin
  • oral mucosa (especially palate) becomes yellow
  • purpuras
  • brownish-red papules
  • non-itching lichenoid alterations (2-6 mm)
  • the tongue becomes atrophic
  • painfully enlarged liver
  • pruritus
26
Q

Hepatitis (therapy)

A

Internal medicine