Topic 53 Flashcards
Chronic Gastritis (etiology)
- prolonged Helicobacter pylory infections
- alcoholism
- hepatitis
- endocrin diseases
- infectious diseases
- autoimmune diseases
Chronic Gastritis (symptoms)
- not always painful
- occasional epigastric pressure
- discomfort
Accompanying symptoms:
- loss of appetite
- nausea
- loss of weight
- abdominal fullness
Chronic Gastritis (oral symptoms)
-erythematous, atrophic oral mucosa
(especially the dorsal surface of the tongue)
-atrophic dorsal lingual surface (lingua fuliginosa)
-glossopyrosis
-increased candidiasis tendency
Chronic Gastritis (differential diagnosis)
- anaemia
- folic acid deficiency
Chronic Gastritis (therapy)
- internal medical treatment
- local antiseptic and analgesic th. (Tantum Verde)
Gastroesophageal reflux disease (etiology)
- Motility problems of the esophagus
- Chronic chemical irritation
- increased risk of dysplastic (precancerous) alterations and epithelial transformation
- increased incidence of adenocarcinoma and epithelial cancers
Gastroesophageal reflux disease (symptoms)
Due to irritative, chemichal effects: - The oral mucosa of the pharynx and - the posterior lingual surface -erythematous -atrophic -erosions -rarely ulcers -coated tongue (yellowish-whitish) -hairy tongue -oropyrosis -glossopyrosis -permanent dental erosions
Gastroesophageal reflux disease (differential diagnosis)
- acute atophic candidiasis
- anemia
- Sjögren’s sy.
Gastroesophageal reflux disease (therapy)
- internal medical treatment
- locally antiseptics
- steroid treatment
Crohn’s disease - terminal ileitis (etiology)
unknown origin - presumably immunpathological disease
Pathogenesis:
- affect the entire digestive system from the oral cavity to the rctum
- extraintestinal, metastatic Crohn’s disease may also occur
- primarily affects the ileum
Crohn’s disease - terminal ileitis (internal symptoms)
- enteritis
- diarrhea
- constipation
- malabsorbtion
- anemia
- arthralgia
Crohn’s disease - terminal ileitis (dermatological symptoms)
- pyoderma vegetans
- erythema nodosum (reddish nodules on the extensor side of the skin of the extremities)
- periorificial erythema
Crohn’s disease - terminal ileitis (oral symptoms)
Pyostomatitis vegetans:
- erythematous and swollen mucosa
- ulcerated, deeply fissured alteration, becomes unevenly „lacerated” and resembles cobble-stone „appearence”:
- hyperplastic, granulomatous, necrotic tissues are easily detachable, and a bleeding area remains without any epithelial layers
- diffuse, red, indurated and granulomatous nodules
evolve on the lips (especially on the upper) and gingiva
- cheilitis granulomatosa (may be the firs sign of Crohn’s disease)
- multiplex fissures on the lips
- pareititis granulomatosa (granulomatous inflammations on the bucca)
- aphtous ulcers, most commonly on the palate
- angular cheilitis
Crohn’s disease - terminal ileitis (differential diagnosis)
- pemphigus vegetans
- granulomas due to candidiasis
- Quincke’s oedema
- granulomatous cheilitis
- hydantoin-hyperplasia
Crohn’s disease - terminal ileitis (therapy)
Internal medical treatment
- corticosteroids
- sulfonamids
- sulphasalazin
- azathioprin (Imuran)
- steroid gél (for the treatment of the oral mucosa)
Ulcerative Colitis (etiology)
-chronic, inflammatory disease of the colon which has an unknown etiology
-commonly accompanied by psychosomatic symptomes
Pathogenesis:
-the disease has a tendency to relapse and then alleviate again
-the disease may be accompanied by hypocromatic anemia, leucocytosis, hypoproteinaemia, increased erythrocyte sedimentation rate
-systemic complications:
*pyostomatitis vegetans
*gangraenous pyoderma
Ulcerative Colitis (oral symptoms)
- non-specific granulomatous alterations
- bleeding, ulcerative, aphtoid and aphtous alterations
- painful deep ulcers and characteristic,hypertrophyc tissue acccumulations make the surface of these alterations uneven and deeply fissured
- yellowish pustules
- desquamativ gingivitis
Accompanied symptoms on the skin:
- nodular erythema
- gangrenous pyoderma
- whitish discoloration of the fingernails(frosted glass nails)
Ulcerative Colitis (therapy)
- internal medicine
- symptomatic treatment locally (susp. anesth., corticosteroid gel)
Celiac disease-enteropathy caused by sensitivity to gluten (etiology)
- genetical faktors
- gluten toxicity
- intestinal peptid deficiency
- immune response
Pathogenesis:
- usually begins in childhood
- symptoms may persist in adulthood as well
- pathological function, malabsorbtion and motility disorders of the small intestine cause:
- GI protein loss
- vitamin deficiencies
- malabsorption of lipids, carbohydrates, water and iron
Celiac disease-enteropathy caused by sensitivity to gluten (symptoms)
- anemia (usually microcytic hypocromatic)
- anorexia
- sore bones
- eczema of the skin
- bleeding tendency
- finger clubbing
Celiac disease-enteropathy caused by sensitivity to gluten (oral symptoms)
- aphtous ulcers (iron and folic acid deficiency) (small aphtae)
- tongue: erythematous, atrophic, burning, painful
- angular cheilitis
- in childhood: dental hypoplasia
Celiac disease-enteropathy caused by sensitivity to gluten (differential diagnosis)
- anemia
- vitamin deficiencies
Celiac disease-enteropathy caused by sensitivity to gluten (therapy)
- primarily internal medical treatment
- gluten-free diet
- combined vitamin substitution
- local antiseptic treatment
Hepatitis (etiology)
- viral infections
- toxic liver damage
- obstruction of biliary pathways - obstructiv jaundice (caused by malignancies or stones)
Details of Pathogenesis:
- vitamin K malabsorption
- hemophylia (purpuras on the face)
- haemorrhage tendencies
- impaired drug metabolism
Hepatitis (symptoms)
- jaundice (commonly the first symptome)
- discoloration not associated to melanin
- caused by bilirubin deposited from the circulation into the sclera and skin
- oral mucosa (especially palate) becomes yellow
- purpuras
- brownish-red papules
- non-itching lichenoid alterations (2-6 mm)
- the tongue becomes atrophic
- painfully enlarged liver
- pruritus
Hepatitis (therapy)
Internal medicine
