Topic 51

Question 1

Riboflavin (B2) deficiency (etiology)

Answer 1

-malnutririon
-malabsorbtion
-alcoholism
-conditions, leading to protein malnutrition
(children not consuming any milk)

Question 2

Riboflavin (B2) deficiency (symptoms)

Answer 2

• Seborrheic dermatitis: * skin
• face
• nasal apertures
• nasolabial folds

Question 3

Riboflavin (B2) deficiency (oral symptoms)

Answer 3

• angular cheilitis:
  in the beginning: yellowis, scaly crusts on the corner of the mouth, then they become red, deep, painfull fissures
  (pebbly appearance),
  they bleed easily
• Tongue: atrophic, magenta in colour, painfull, fissured

Question 4

Riboflavin (B2) deficiency (differential diagnosis)

Answer 4

-anemia caused by
iron deficiency
-chronic atrophic
candidiasis

Question 5

Riboflavin (B2) deficiency (therapy)

Answer 5

• riboflavin

Question 6

Nicotinamide (B3) deficiency-pellagra

etiology

Answer 6

• protein malnutrition
• anacidity
• gastroenteritis
• congenital metabolic disorders
• chronic alkoholism

Question 7

Nicotinamide (B3) deficiency-pellagra

symptoms

Answer 7

• loss of appetite
• weakness
  In more evolved cases:
• dermatitis
• dementia
• diarrhea

Question 8

Nicotinamide (B3) deficiency-pellagra

oral symptoms

Answer 8

Tongue:

• atrophic filiform papillae
• swollen
• painful
• burning
• red, resembles „raw meat”

Question 9

Nicotinamide (B3) deficiency-pellagra

differential diagnosis

Answer 9

• pernicious anaemia
• anaemia caused by
  iron deficiency
• Sjögren’s sy.

Question 10

Nicotinamide (B3) deficiency-pellagra

therapy

Answer 10

• Substitution of

nicotinic acid

Question 11

Folic acid (B6) deficiency (etiology)

Answer 11

- imbalanced nutrition
(vegetables and fruits)
- malabsorption
(celiac disease)
- alcoholism
- anorexia
- cancerous disease
- pregnancy
- hemolytic anaemia
- medication
(contraceptives, phenytoin, anticonvulsive drugs)
- accompanied by the lack of vit. B12
- The lack of folic acid demages
protein synthesis and cell division

Question 12

Folic acid (B6) deficiency (symptoms)

Answer 12

• erythemas
• atrophic, painful tongue
  (filiform, fungiform papillae disappear)
• aphtous ulcers
• angular cheilitis

Question 13

Folic acid (B6) deficiency (diagnosis)

Answer 13

• serum folic acid and B12 levels

Question 14

Folic acid (B6) deficiency (differential diagnosis)

Answer 14

• Anaemia

- Other B vit. deficiencies

Question 15

Folic acid (B6) deficiency (therapy)

Answer 15

• substitution of folic acid and B12

- local symptomatic treatment

Question 16

Vitamin C deficiency-scurwy

etiology

Answer 16

• insufficient nutrition
  (poverty, elderly age, chronic alcoholism)
  1. In infancy or chilhood: Möller-Barlow disease
  -disturbances of bone development
  2. In adults
  -demaged collagen synthesis
  -failed connective tissue regeneration

Question 17

Vitamin C deficiency-scurwy

symptoms

Answer 17

• hyperkeratotic hair follicule

- perifollicular bleeding

Question 18

Vitamin C deficiency-scurwy

oral symptoms

Answer 18

• swollen gingiva
  (cover the crown)
• easy or spontaneusly
  bleeding gingiva
• pain of mandibular bones
• gingiva necrosis around bleeding area
• accompany oral odor and fusospirochaetal stomatitis
  (cause swift destruction of alveoli and loss of teeth)
• patients without teeth have not oral symptomes except bleeding
• ulcerativ stomatitis (also by patient without teeth
• TMJ haemorrhage

Question 19

Vitamin C deficiency-scurwy

diagnosis

Answer 19

• Rumpel-Leede sign is positive

Question 20

Vitamin C deficiency-scurwy

differential diagnosis

Answer 20

• ulcerative, necrotising,
  herpetic gingivostomatitis
• leukaemia
• agranulocytosis

Question 21

Vitamin C deficiency-scurwy

therapy

Answer 21

• ascorbic acid