Topic 4 (Saliva) Flashcards
A dilute aqueous solution , a solvent, with organic and inorganic contents
Salivary Secretion
What are the functions of Salivary Secretion:
- Bolus formation
- Food lubrication for easy swallowing and
speech production - Maintain good oral health – most important
What is the most important function of salivary secretion?
Maintain Good Oral Health
What are the other functions of saliva:
- Secrete nerve growth factor
- Secrete vasoactive peptides
- Secrete regulatory peptides
What is saliva’s important role in the alimentary tract?
Protect the teeth & buccal mucosa from bacterial attack
What are the Major Functions of the Saliva:
- Lubrication
- Digestion
- Solvent Action
- Antibacterial Action
- Antifungal Action
- Buffering Action
- Remineralization
- Temperature Regulation
- Production of Growth Factors & Other Regulatory Peptides
Dry mouth
Xerostomia
Xerostomia (dry mout ) will cause bad odor because without saliva, bacteria will act on food debris causing it to decompose
Buffering Action of Saliva
It will cause bad odor because without saliva, bacteria will act on food debris causing it to decompose
Xerostomia
The bacterial products will not be diluted and ____ is lost , thus increase in caries.
buffering action of saliva
A digestive enzyme responsible for the initial breakdown of starch and glycogen
Salivary Amylase
It has the highest concentration in saliva
Salivary Amylase
Remains active in the stomach because it is
protected inside the food bolus.
Salivary Amylase
Secreted by the lingual salivary glands (Von Ebner’s glands)
Salivary Lipase
Responsible for the first step in fat digestion
Salivary Lipase
Important in fat digestion
Salivary Lipase
Is active inside the stomach’s pH
Salivary Lipase
In 1 day ____ to ____ of fluid is produced
0.5 to 0.75
In 1 day, some salivary components are from
____ while some are synthesized in the salivary glands.
blood plasma
In 1 day, some salivary components are from blood plasma while some are synthesized in the ____.
salivary glands
Most of the fluid is ____ and ____ by the gut.
swallowed and reabsorbed
Most of the fluid is swallowed and reabsorbed by the ____.
gut
What are the three main salivary gland:
- Parotid gland
- Submaxillary (submandibular) gland
- Sublingual gland.
The 3 main salivary glands; they secrete ____% of total saliva
90%
What are the other salivary glands:
- Lingual salivary glands found in the tongue (called Von Ebner’s glands)
- Labial glands, Palatine glands, Buccal glands (cheek)
Other Lingual salivary glands found in the tongue is called ____.
Vin Ebner’s Glands
cheek
Buccal Glands
Composition of Saliva Made of:
- Ions
- Organic Components
- Water (99%)
chloride, bicarbonate are examples of:
Anions
sodium, potassium are examples of:
Cations
What are other electrolytes that are included:
- calcium phosphate
- fluoride
- thiocyanate
- magnesium sulfate
- iodine
Anions and Cations are derived from ____.
Blood Plasma
Important because it is the chief butter of saliva.
Bicarbonate
Caries occur due to low pH of saliva.
Bicarbonate
Caries occur due to ____ of saliva.
low pH
if the saliva pH is lowered (acidic) it will decalcify teeth, resulting to ____.
caries
if the saliva pH is lowered (acidic) it will ____.
decalcify teeth, resulting to caries.
if the saliva pH is lowered it is ____.
Acidic
The concentration of the ____ in saliva increases with the flow rate of saliva
bicarbonate
Increased flow rate of saliva =
Increased Bicarbonate
Increased Bicarbonate =
increased pH
increased pH =
resulting to alkaline saliva
Alkaline saliva =
Less dental caries
As the rate of salivary flow increases, the % of ____ also increases.
salts
As the rate of salivary flow increases, the % of salts also increases.
Heidenhain’s Law
As salivary flow increases, the composition of saliva also changes.
Heidenhain’s Law
As salivary flow increases, the composition of saliva also ____.
changes
But not all components will increase.
- Sodium (Na+)
- Potassium (K+)
- Sodium (Na+) increases
- Potassium (K+) decreases
Cells found in the secretory unit of the salivary gland, lies close to the acini & intercalated ducts.
Myoepithelial Cells
The cytoplasm of the myoepithelial cell contains ____ capable of contraction.
filaments
Innervated by both parasympathetic and sympathetic nerve fibers
Myoepithelial Cells
Activation of the ANS causes these cells to contract, thus saliva will be expelled from salivary glands.
Myoepithelial Cells
Activation of the ANS causes these cells to ____, thus saliva will be expelled from salivary glands.
contract
Peripheral reflex phenomenon
Stimulation of Afferent Nerves
Can cause the release of saliva
Stimulation of Afferent Nerves
Different tastes can also induce saliva to flow
when placed on the tongue.
Stimulation of Afferent Nerves
____ can also induce saliva to flow
when placed on the tongue.
Different tastes
The most effective taste of which is:
sour taste particularly citric acid
control its flow
Autonomic nerves
exerted by saliva is lower than serum
Osmotic pressure (tonicity)
____ increases as flow rate of saliva increases
Tonicity
Saliva contains potassium ions ____ to ____ times the
concentration of serum potassium.
2 to 10
Saliva in many animals contains a high level of the ____ and other macromolecules.
digestive amylase
It is made of numerous secretory units which is
made of:
- Intercalated duct
- Acinus
- Striated duct
- Excretory duct
Saliva forms at the ____ where the acini is located
proximal end of the duct
Acini is located at the ____.
proximal end of the duct
The acini is made of ____.
acinar cells
the main bulk of the salivary gland
acinar cells
cells which surrounds the acini & intercalated ducts. These cells have filaments which have contractile properties
Myoepithelial cells
What are the other structure in the Salivary Gland:
- Myoepithelial cells
- Blood Supply
- Nerve Supply
Saliva’s Organic Components Function:
- Enzymatic function
- Coating of tissue surfaces
- Protection of dental tissues
- Control of tissue growth
All oral soft tissues are coated with ____, which traps ____, which binds strongly to ____ thus ____ is formed.
All oral soft tissues are coated with mucous glycoproteins, which traps bacteria, which binds strongly to tooth surface thus enamel pellicle is formed.
Decrease flow of saliva =
decrease buffering effect
decrease buffering effect =
increase caries
Occurs when food is placed in the mouth
Salivary Reflexes
Occurs even when mouth is anesthesized
Salivary Reflexes
This reflex is due to stimulation of periodontal
receptors & taste receptors
Salivary Reflexes