Topic 3B - More Exchange And Transport Systems Flashcards
Define digestion
The hydrolysis of large, insoluble molecules into smaller molecules that can be absorbed across the cell membranes
Which enzymes are involved in carbohydrate digestion
Amylase found in the mouth
Maltase sucrase and lactase found in the membrane of small intestine
What are the substrates and products of the carbohydrate digestive enzymes
Amylase - starch into smaller polysaccharides
Maltase - maltose into 2 glucose
Sucrase - sucrose into glucose and fructose
Lactase - lactose into glucose and galactose
Where are lipids digested
The small intestine
What needs to happen before lipids can be digested
They must be emulsified by bile salts produced by the liver. This breaks down large fat molecules into smaller, soluble molecules called micelles, increasing the surface area.
How are lipids digested
Lipase hydrolyses the ester bond between the monoglycerides and fatty acids
Which enzymes are involved in protein digestion? What area their roles?
Endopeptidases - break between specific amino acids in the middle of a polypeptide
Exopeptidases - break between specific amino acids at the end of a polypeptide
Dipeptidases - break dipeptides into amino acids
Which molecules require co-transport
Amino acids and monosaccharides
Explain how sodium ions are involved in co-transport
Sodium ions are actively transported out of the cell into the lumen, creating a diffusion gradient. Nutrients are then taken up into the cells along with Na+ ions
Describe the structure of haemoglobin
Globular, water soluble, consists of 4 polypeptide chains, each carrying a haem group
Describe the role of haemoglobin
Present in RBC. Oxygen molecules bind to the haem groups and are carried around the body to where they are needed in respiring tissues
Name three factors affecting oxygen-haemoglobin binding
- Partial pressure / conc of oxygen
- Partial pressure / conc of carbon dioxide
- Saturation of haemoglobin with oxygen
How does partial pressure of oxygen affect oxygen-haemoglobin binding
As partial pressure increases, the affinity of haemoglobin for oxygen also increases, so oxygen binds tightly to haemoglobin. When partial pressure is low, oxygen is released from haemoglobin
How does partial pressure of carbon dioxide affect oxygen-haemoglobin binding?
As partial pressure of carbon dioxide increases, the conditions become acidic causing haemoglobin to change shape. The affinity of haemoglobin for oxygen therefore decreases, so oxygen is released from haemoglobin. This is known as the Bohr effect
Explain why oxygen binds to haemoglobin in the lungs
Partial pressure of oxygen is high
Low concentration of carbon dioxide in the lungs so affinity is high
Explain why oxygen is released from haemoglobin in respiring tissues
Partial pressure of oxygen is low
High concentration of carbon dioxide in respiring tissues, so affinity decreases
What does the oxyhaemoglobin dissociation curve show
Saturation of oxygen against the partial pressure of oxygen
How does carbon dioxide affect the position of an oxyhaemoglobin dissociation curve
Curve shifts to the right because haemoglobin affinity for oxygen has decreased
What is the structure of the atria and ventricles and how does it help to perform its function
Atria: Thin, elasticated walls so they can stretch when filled with blood, increasing the force of contraction
Ventricles: thick muscular walls pump blood under high pressure. The left ventricle is thicker than the right because it has to pump blood all the way around the body
What is the structure and function of the arteries
Thick walls - handle high pressure without tearing
Muscular and elastic - to control blood flow