Topic 32: Togaviridae (Toga-Roman mantle, cloak) and Flaviviridae (Flavus-yellow) –

Question 1

Topic 32: Togaviridae (Toga-Roman mantle, cloak) and Flaviviridae (Flavus-yellow)
TOGAVIRIDAE:

Answer 1

• Genera:
• Alpha-,
• Rubvirus genus.
• Morphology: Linear +ssRNA, enveloped capsid.
• Resistance: weak.
• Biological properties:
• Baltimore IV.
• NO CPE!
• Antigenic properties: Good antigens, cross reaction.
• Diagnosis:
• Alphavirus genus:
  Equine encephalitis. (Mosquito)
  Severe cases of EEE (involving encephalitis, an inflammation of the brain) begin with the sudden onset of headache, high fever, chills, and vomiting. The illness may then progress into disorientation, seizures, or coma.
  Semliki forest virus (Africa).
• Rubvirus genus: Rublla – Human.

Question 2

Topic 32: Togaviridae (Toga-Roman mantle, cloak) and Flaviviridae (Flavus-yellow)
TOGAVIRIDAE
Simple

Answer 2

• Genera:
• Alpha-,
• Rubvirus genus.
• Linear +ssRNA, enveloped capsid.
• Weak resistance
• Biological properties:
• Baltimore IV.
• NO CPE!
• Good antigens, cross reaction.
• Diagnosis:
• Alphavirus genus:
  Equine encephalitis (Mosquito)
  Semliki forest virus (Africa).
• Rubvirus genus: Rublla – Human.

Question 3

Topic 32: Togaviridae (Toga-Roman mantle, cloak) and Flaviviridae (Flavus-yellow)
FLAVIVIRIDAE:

Answer 3

• Genera:
• Flavi-,
• Pesti,
• Hepacivirus genus.
• Morphology: Linear +ssRNA, enveloped capsid.
• Resistance: weak.
• Biological properties:
• Baltimore IV – single polyprotein.
• Flavivirus – arbovirus (mosquito or tick).
• Antigenic properties: Good antigens, cross reaction.
• Diagnosis:
  Flavivirus genus – Yellow fever in Humans.
  Pestivirus genus – Classical swine fever.
  Hepacivirus genus – Hepatitis C in humans.

Question 4

Topic 32: Togaviridae (Toga-Roman mantle, cloak) and Flaviviridae (Flavus-yellow)
FLAVIVIRIDAE:
Simple

Answer 4

• Flavivirus genus – Yellow fever in Humans.
• Pestivirus genus – Classical swine fever.
• Hepacivirus genus – Hepatitis C in humans.
• Linear +ssRNA, enveloped capsid.
• Weak resistance
• Biological properties:
• Baltimore IV – single polyprotein.
• Flavivirus – arbovirus (mosquito or tick).
• Good antigens, cross reaction