Topic 25: Papillomaviridea, Polyomaviridea, Adenoviridea

Question 1

Topic 25: Papillomaviridea

Answer 1

Papillomaviridea (Papilla=wart, oma=tumor):

• Genus: papillomavirus.
• Morphology: Circular dsDNA, superhelical.
• Resistance: STRONG.
• Biological properties:
  Baltimore I.
  Oncogenic – Benignant tumors.
• Antigenic properties:
  Good antigen (hidden from immune system)  auto vaccines.
  No cross-reaction.
• Diagnosis (Clinical signs, IF, EM):
  Equine – head and nose.
  Bovine – neck back and body.

Question 2

Topic 25: Polyomaviridea

Answer 2

Polyomaviridea
(Poly=many, oma=tumor)

• Genus: Polyomavirus.
• Morphology: Circular dsDNA, superhelical.
• Resistance: STRONG.

* Biological properties:
Baltimore I.
Oncogenic – SV40 model virus.
Airborne.
Microtumors in cell culture.

Question 3

Topic 25: Adenoviridea (adenos – adenoid gland):

Answer 3

Adenoviridea (adenos – adenoid gland):

• Genera: Mastadeno-, Aviadeno-, Atadeno, and Siadenovirus.
• Morphology: Linear dsDNA, no envelope.
• Biological properties:
  Baltimore I.
  Oncogenic – apoptosis inhibition.
• Antigenic properties:
  Good antigens.
  Cross-reaction.
• Diagnosis: Isolation –
  I) Mastadenovirus:
  Pneumoenteritis of calves and lamb.

II) Aviadenovirus:
Inclusion body hepatitis, gizzard eruption.
Symptoms - Jaundice and anemia.

III) Atadenovirus:
Pneumoenteritis of calves, EDS.

Pneumoenteritis:
Inflammation of the lungs and intestine.

IV) Siadenovirus:
Frog adenovidus.

Question 4

short - Summary:

Papillomaviridea

Answer 4

Papiloma virus - papilla=wart - oma=tumor
Circular dsDNA, superhelical.
Clinical signs:
- Warts
Canine - Mouth, ears
Equine – head and nose.
Bovine – neck back and body.
- Imunesystem

Question 5

short - Summary

Polyomaviridea

Answer 5

Polyoma virus
(Poly=many, oma=tumor)
Circular dsDNA, superhelical.

Question 6

short - Summary

Adenoviridea (adenos – adenoid gland):

Answer 6

• Genera: Mastadeno-, Aviadeno-, Atadeno, and Siadenovirus.

Linear dsDNA, no envelope.
* Diagnosis: Isolation –

• M:
  Mastadenovirus:
  Pneumoenteritis of calves and lamb.
• A:
  Aviadenovirus:
  Inclusion body hepatitis, gizzard eruption.
  Symptoms - Jaundice and anemia.
• At:
  Atadenovirus:
  Pneumoenteritis of calves, EDS.

Pneumoenteritis =
Inflammation of the lungs and intestine.