Topic 3 Part 2 Flashcards
Hämoglobin
-Groups of proteins found in diffrent organism
-Quaternary structure
-Has red blood cells transport of oxygen
Oxyhaemoglobin dissociation curve
Oxygen is loaded in regions with high partial pressure of oxygen
-alveoli
Oxygen is unloaded in regions of low partial pressure
-respiring tissues
Cooperative binding
Oxygen Binding to haemoglobin is due to haemoglobin changing shape when the first oxygen binds
Makes it easier for the rest of oxygen to bind
Bohr effect
High co2 conc causes oxyhaemoglobin curve to shift to the right
Affinity for oxygen decreases because the acidic carbon dioxide changed the shape of haemoglobin slights
Lower ph more co2 present
Low partial pressure of co2 in alveoli curve shift left increased affinity of oxygen uploads more oxygen
High partial pressure of co2 at respiring tissue . Curve shifts right decreased affinity and unloads more oxygen
Animals have diff haemoglobin which have diffrent affinities for oxygen
Adaption to their environment
Human foetus
Hbf - hemoglobin
Hugh affinity for oxygen at same partial pressure as adult
Advantage foetus
Blood circulating through cord foetus haemoglobin load the oxygen off the mothers adult haemoglobin
Llama
Found at high altitude
Low partial pressure of oxygen
Also have haemoglobin higher affinity for oxygen even at lower partial pressure
If no oxygen available haemoglobin still able to load up
Dove
Need more oxygen to match fast metabolism for respiration to provide energy for contracting muscles
Curve shift to the right hemoglobin lower affinity for oxygen
Readily unload oxygen needed for respiration
Earth worms
Underground
There is lower partial pressure of oxygen
Haemoglobin high affinity
Load up with oxygen available
Double circularity system
Closed - blood remains within the blood vessels
Blood passes through heart twice
- delivers blood to the lungs
- delivers blood to rest of the body
Mammals double circularity system
Manage pressure of blood flow
Blood flow through lungs at lower pressure
Prevents damage to capillaries in the alveoli and also reduces speed
More time for gas exchange
Oxygenated blood from lungs then goes back through the heart to the pumped at a higher pressure to the rest of the body
Coronary arteries
Supply the cardiac muscle with oxygenated blood .
Branch of the aorta
Get blocked heart attack
Cardiac muscle
The walls of the heart have a thick muscular layer
Myogenic - can contract and relax without nervous or hormonal stimulation
Never fatigues as long as it have a supply of oxygen
Blood vessels
Arteries - carry blood away from heart into arterioles
Arterioles - smaller than arteries and connect to the capillaries
Capillaries connected the arterioles to the veins
Veins carry blood into the wart