Topic 3: Mendelian Genetics Flashcards
why did Mendel choose peas for his experiment?
- flowers have male and female structures
- self-fertilise
- can use artificial cross-fertilization
- short life cycles
what are test crosses ALWAYS crossed with?
homozygous recessive x F1
what is the genotypic ratio for a monohybrid cross? phenotypic?
1:2:1, 3:1
what is Mendel’s first law?
Law of Segregation, two alleles from the same gene separate from one another during the formation of gametes (meiosis I, occurs during anaphase I)
self-fertilization of the F2 produces a ____ phenotypic ratio
3:1
dihybrid crosses support Mendel’s second law, what is it?
Independent assortment (the segregation of alleles of one gene are independent of the other, occurs during metaphase)
dihybrid crosses: crossing the F1 heterozygotes produce a _____ phenotypic ratio in the F2
9:3:3:1
____: two independently assorting traits
dihybrid cross
____: three independently assorting traits
trihybrid cross
_____: the probability that 2 independent outcomes will BOTH occur
product rule (multiply them)
_____: the probability that either one or the other of two independent outcomes will occur
sum rule (two traits are mutually exclusive)
________: suggests that there is no statistically significant difference between the observed outcome and the expected outcome
H0, null hypothesis
________: suggests that there is a statistically significant difference between the observed outcome and the expected outcome
Ha, alternative hypothesis
step 1: define H0 and Ha
step 2: define alpha value (0.05)
step 3: calculate observed numbers, expected numbers, chi-square value, and degrees of freedom
step 4: compare those numbers to critical value
step 5: draw conclusions
these are all steps of which test?
chi-square analysis