topic 3 Flashcards

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1
Q

small organisms

A

-large SA:V
-large SA means big surface for exchange of substances
-small diffusion pathway for substance exchange
-therefore, very small organisms can simply exchange substances across their surface.

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2
Q

large organisms

A

-smaller SA:V and higher metabolic rate so demand for efficient exchange of substances is higher
adaptations to increase SA:V
-villi and microvilli for efficient absorption of digested food
-alveoli and bronchioles for gas exchange in animals
-spiracles and tracheoles for gas exchange in insects
-gill filaments and lamellae for gas exchange in fish
-thin wide leaves for gas exchange of plants
-many capillaries for substance exchange in blood

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3
Q

fish adaptations

A

-large SA:V created by many gill filaments covered by many gill lamellae for efficient gas exchange.
- short diffusion distance due to very thin gill lamellae
-concentration gradient Is maintained due to counter-current flow mechanism.
-counter-current flow is when water flows over the gills in the opposite direction to the flow of blood in the capillaries.
-this ensures that equilibrium is not reached so a diffusion gradient is maintained across the entire length of the gill lamellae.

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4
Q

insect adaptations

A

to reduce water loss:
-small SA:V for water to evaporate
-waterproof exoskeleton
-spiracles where water can evaporate from, can open and close to reduce water loss.
for gas exchange:
-developed a system of breathing tubes that deliver oxygen directly to all tissue and organs.
-air enters body via external opening called spiracles
-these lead to tubes called tracheae and tracheoles.
-tubes have rigid rings to keep them open
-spiracles are sunken which traps moisture to prevent further evaporation.
-lots of tracheoles so large SA for diffusion of gases
-walls of tracheoles are thin and there is a short distance between spiracles and tracheoles so short diffusion pathway.
-the absorption of O2 and production of CO2 sets up a steep conc gradient

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5
Q

proteases

A

-produced in stomach, pancreas and ileum of small intestine.
-used in stomach and duodenum & ileum of small intestine
-endopeptidases hydrolyse peptide bonds between specific amino acids in the middle of a polypeptide to form dipeptides and tripeptides.
-exopeptidases hydrolyse peptide bonds between specific amino acids at the ends of a polypeptide to produce dipeptides or individual amino acids.
-membrane-bound dipeptidases hydrolyse the peptide bond in a dipeptide.

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6
Q

carbohydrases

A

-produced in salivary glands, pancreas and small intestine
-used in mouth and duodenum & ileum of small intestine
-salivary glands secretes saliva containing amylase into the buccal cavity. this catalyses the hydrolysis of starch into maltose.
-in the duodenum, pancreatic amylase is secreted which catalyses the hydrolysis of any undigested starch into maltose.
-in the ileum, membrane-bound maltase breaks down maltose into glucose

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7
Q

lipases

A

-produced in the pancreas
-used in the duodenum of the small intestine
-lipases break down triglycerides and phospholipids to produce a glycerol molecule + 3 fatty acids or a glycerol molecule + 2 fatty acids + phosphate group
-large lipid droplets entering the small intestine are broken down by agitation

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8
Q

bile salt molecules

A

-hydrophobic tail and negatively charged hydrophilic head
-lipid droplets are emulsified by bile salts in bile to form a lipid emulsion
-bile is made in the liver and stored in the gall bladder
-the gall bladder contracts to release bile into the duodenum
-emulsification stops lipid droplets from forming larger droplets so increases SA for lipase to efficiently digest the triglycerides
-the emulsion droplets are soluble in water
-pancreatic lipase catalyses the hydrolysis of triglycerides at the surface of the emulsion droplets forming monoglycerides, glycerol and fatty acids.
-these products are insoluble in water
-the products combine with bile salts to form small water-soluble molecules called micelles.
-the molecules that make up micelles are clustered together with their polar ends facing the surface of the micelles making it soluble
-they transport the fatty acids, monoglycerides and glycerol to the epithelial cells of the intestine wall and release them for absorption.
-micelles fit between the microvilli
-the individual monoglycerides and fatty acids diffuse through the cell membrane
-they are turned into triglycerides in the SER
-the Golgi apparatus processes triglycerides and combines them with proteins forming lipoproteins.
-these are then packaged for release and transported through lymphatic vessels

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9
Q

how do sodium ions normally enter the blood

A

active transport using ATP or carrier proteins:
the Na+ - glucose symporter - the pump which moves glucose and Na+ across the epithelial cell membrane together (co-transport)
the sodium - potassium pump - uses ATP to move sodium ions out of the cell and potassium ions into the cell

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10
Q

structures and functions of the human gaseous exchange system

A

cartilage- prevents collapse of airways under low pressure when breathing in
ciliated epithelium - involved in moving
mucus along to prevent lung infection by moving it towards the throat where it can be swallowed.
Goblet cells – involved in mucus secretion to trap bacteria and dust to reduce the risk of infection with the help of lysozymes which digest bacteria
squamous epithelium- smooth and thin for shorter diffusion path
smooth muscle- constrict airways to protect alveoli
elastic fibres - allow alveoli to stretch and spring back during exhalation

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11
Q

gaseous exchange definition

A

the diffusion of oxygen from the air in the lungs into the blood and CO2 from the blood into the air in the lungs

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12
Q

why we need so much O2

A

humans are relatively large organisms with a large number of living cells
to maintain a constant body temp, metabolic and respiratory rates

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13
Q

overall structure of the human gaseous exchange system

A

alveoli, bronchioles, bronchi, trachea, lungs

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14
Q

features of alveolar epithelium which allow efficient gas exchange

A

-many small alveoli give large surface area to volume ratio
-walls only one layer of squamous epithelial cells giving a short diffusion distance
-cell surface membranes of alveolar epithelium are partially permeable
-The constant blood supply by capillaries means that a steep concentration gradient is constantly maintained.
-elasticity of walls means they strech and recoil to expel air during exhalation

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15
Q

ventilation definition

A

The flow of air in and out of the alveoli is referred to as ventilation and is composed of two stages; inspiration and expiration

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16
Q

inspiration

A

During inspiration, the external intercostal muscles contract whereas the internal muscles relax, as a result this causes the ribs to raise upwards. The diaphragm contracts and flattens. In combination, the intercostal muscles and diaphragm cause the volume inside the thorax to increase, thus lowering the pressure. The difference between the pressure inside the lungs and atmospheric pressure creates a gradient, thus causing the air to be forced into the lungs.

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17
Q

expiration

A

During expiration, the internal intercostal muscles contract whereas the external muscles relax therefore lowering the rib cage. The diaphragm relaxes and raises upwards. This action in combination decrease the volume inside the thorax, therefore increasing the pressure, forcing the air out of the lungs.

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18
Q

spirometer

A

a device used to measure lung volume. A person using a spirometer breathes in and out of the airtight chamber, thus causing it to move up and down, leaving a trace on a graph which can then be interpreted.

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19
Q

vital capacity

A

the maximum volume of air that can be inhaled or exhaled in a single breath.

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20
Q

Tidal volume

A

the volume of air we breathe in and out at each breath at rest

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21
Q

Breathing rate

A

the number of breaths per minute. It can be calculated from the spirometer trace by counting the number of peaks or troughs in a minute

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22
Q

residual volume

A

The volume of air which is always present in the lungs

23
Q

expiratory reserve volume

A

the additional volume of air that can be exhaled on top of the tidal volume.

24
Q

arteries

A

-carry blood from the heart to the rest of the body
-thick muscular walls with elastic tissue which stretches and recoils as the heart beats, helping to maintain high pressure
-folded inner lining allowing the artery to stretch and maintain high pressure
-all arteries carry oxygenated blood except for the pulmonary artery which carries deoxygenated blood from the heart to the lungs.

25
Q

arterioles

A

-arteries divide into arterioles
-they form a network throughout the body
-there are muscles inside the arterioles to direct blood wherever it is needed.
-the muscles contract to restrict blood flow and relax to allow full blood flow.

26
Q

veins

A

-take blood back to the heart under low pressure
-wider lumen than arteries
-very little elastic or muscle tissue
-contains valves to stop blood flowing backwards
-body muscles around the veins aid the transport of blood
-all veins carry deoxygenated blood except for the pulmonary vein which carries oxygenated blood from the lungs to the heart

27
Q

capillaries

A

-smallest blood vessel
-substances are exchanged between cells and capillaries
-always found near cells in exchange tissues so there is a short diffusion pathway
-walls are only one cell thick which also shortens diffusion pathway
-lots of capillaries to increase surface area for exchange

28
Q

what is tissue fluid?

A

-fluid that surrounds cells in tissues
-made from small molecules that leave the blood plasma
-doesn’t contain red blood cells or large proteins as they are too big to pass through capillary walls
-cells take in oxygen and nutrients from the tissue fluid and release metabolic waste (CO2) into it

29
Q

how is tissue fluid formed?

A

-at the arteriole end of the capillaries, the hydrostatic pressure is greater inside the capillaries than outside
-this leads to an overall outward pressure which forces fluid out of the capillaries and into the spaces surrounding the cells, forming tissue fluid
-as the fluid leaves, the hydrostatic pressure in the capillaries reduces so hydrostatic pressure is much lower at the venule end of the capillaries
-due to the loss of fluid, the concentration of plasma proteins which are too big to leave the capillaries increases so the water potential at the venule end of the capillaries is lower than the tissue fluid
-this means some water re-enters the capillaries from the tissue fluid at the venule end by osmosis.
-any excess tissue fluid is drained into the lymphatic system which transports the excess fluid from the tissues back to the circulatory system.

30
Q

left ventricle adaptations

A

-thicker more muscular walls than the right ventricle because it needs to contract powerfully to pump blood all around the body whereas the right side only needs to pump blood to the lungs.

31
Q

ventricles adaptations

A

-thicker walls than the atria as they push blood out of the heart whereas the atria just need to push blood to the ventricles

32
Q

AV valves function

A

-AV valves link the atria to the ventricles and stop blood flowing back into the atria when the ventricles contract

33
Q

semi lunar valves function

A

-link the ventricles to the pulmonary artery and aorta and stop blood flowing back into the heart after the ventricles contract.

34
Q

cords function

A

-attach AV valves to the ventricles to stop them being forced up in the atria when the ventricles contract

35
Q

atrial systole

A

-ventricles relax atria contract
- volume of atria decreases so pressure increases, pushing blood into ventricles so AV valves open
-semi-lunar valves are closed
-the volume and pressure in the ventricles increases slightly

36
Q

ventricle systole

A

-atria relax ventricles contract
-volume of ventricles decreases so pressure increases
-pressure is higher in the ventricles than in the atria so the AV are forced shut to prevent backflow
-pressure is also higher in the ventricles than the aorta and pulmonary artery, forcing open the semi lunar valves so blood flows out of the heart through these arteries

37
Q

diastole

A

-ventricles and atria both relax
-higher pressure in the pulmonary artery and aorta so the semi lunar valves close to prevent backflow into the ventricles
-blood returns to the heart and flows into the atria due to the high pressure of the vena cava and pulmonary vein
-pressure of the atria then begins to increase
-as ventricles continue to relax, their pressure falls below the pressure of the atria so AV valves open and blood flows passively into the ventricles from the atria
-the atria contract and the process repeats

38
Q

the formation of atheromas

A

-fatty deposits on the inner wall of arteries
-if the endothelium (inner layer of arteries) becomes damaged by high blood pressure, white blood cells and lipids from the blood clump together under the lining to form fatty streaks.
-over time, lipids, white blood cells and other materials build up to form a fibrous plaque called an atheroma
-this partially blocks the lumen of the artery and restricts blood flow causing blood pressure to increase

39
Q

atherosclerosis and CHD

A

-atherosclerosis is a condition when there is a build-up of lipid plaques in arteries. atheromas are formed as a consequence.
-it can lead to coronary heart disease when the coronary arteries have a lot of atheromas in them, restricting blood flow to the heart muscle

40
Q

aneurysm

A

-atheroma plaques damage and weaken arteries as well as narrow them causing blood pressure to increase
-when blood flows through a damaged artery- especially at high pressure- it may push the inner layers of the artery through the outer elastic layer to form a balloon-like swelling- an aneurysm
-the aneurysm may burst causing a haemorrhage (bleeding)

41
Q

thrombosis

A

-if an atheroma plaque ruptures the endothelium of an artery, the artery wall becomes damaged and leaves a rough surface.
-this causes platelets to accumulate at the site and form a blood clot
-the blood clot can cause a complete blockage of the artery, which can cause a stroke or it can become dislodged and block blood vessel elsewhere in the body.
-debris of the rupture can cause another blood clot to form further down the artery

42
Q

myocardial infarction

A

-coronary arteries surround the heart
-they provide blood to supply the heart muscles with oxygen they need to respire
-if there is a blood clot in the coronary artery, an area of the heart muscle will receive no oxygen.
-this causes a myocardial infarction (heart attack)
-a heart attack can cause damage and death of the heart muscle
-symptoms include pain in the chest and upper body, shortness of breath and sweating
-if large areas of the heart are affected, heart failure may occur which is often fatal.

43
Q

factors increasing the chance of cardiovascular diseases

A

high blood cholesterol- cholesterol is one of the main components of the fatty deposits that form atheromas. avoid diets high in saturated fat
smoking- nicotine increases risk of high blood pressure. carbon monoxide binds with haemoglobin and reduces amount of oxygen transported in the blood so the heart muscle receives less oxygen which could lead to a heart attack. smoking decreases the amount of antioxidants in the blood so cell damage in the artery is more likely. this can lead to atheroma formation.
high blood pressure- increases risk of damage to artery walls. this increases risk of atheroma formation so blood pressure increases even further. atheromas can also cause blood clots to form which can lead to myocardial infarction. associated with being overweight, not exercising and excessive alcohol consumption

44
Q

function of xylem tissue

A

-made up of dead cells
-transports water and mineral ions in solution
-the substances move up from root to leaves

45
Q

function of phloem tissue

A

-transports organic substances like sugars up and down the plant
-xylem and phloem are mass transport systems

46
Q

cohesion tension theory

A

-water evaporates from leaves at the top of the xylem (transpiration)
-this creates tension which pulls more water up the xylem into the leaf
-water molecules are cohesive so the whole column of water in the xylem moves upwards

47
Q

transpiration

A

-the evaporation of water from a plant’s surface
-water evaporates from the moist cell walls and accumulates in the spaces between the cells in the leaves
-when the stomata open, the water moves out of the leaf down the concentration gradient

48
Q

factors that affect transpiration rate

A

-light: stomata open to photosynthesise when there is more light which allows water to leave
-temperature: warmer water molecules have more energy so they evaporate faster
-humidity: lower humidity=faster transpiration rate. if the air is dry, the conc gradient is steeper
-wind: lots of air movement blows the water molecules out of the stomata so transpiration increases

49
Q

how to use a potometer

A

-cut a shoot underwater to prevent air from entering the xylem
-cut it at a slant to increase the surface area for water uptake
-assemble the potometer in water and insert the shoot in water so no air can enter
-remove the apparatus from the water but keep the end of the capillary tube submerged in a beaker of water
-make sure the apparatus is airtight and watertight
-dry the leaves, allow time for the shoot to acclimatise and then shut the tap
-remove the end of the capillary tube from the beaker of water until one air bubble has formed, then put the end of the tube back into the water
-record the starting position of the air bubble
-start a stopwatch and record the distance moved by the bubble per unit time
-the rate of air bubble movement is an estimate of the transpiration rate

50
Q

seive tube elements

A

-seive tube elements are living cells that form the tube of the phloem for transporting solutes
-each seive tube has a companion cell to provide ATP for active transport of substances

51
Q

translocation

A

-the movement of solutes to where they are needed in the plant.
-requires energy and occurs in the phloem
-moves solutes from sources to sinks
-sources= where its made (high conc)
-sinks=where it is used up (low conc)
-enzymes maintain the conc grad by breaking down solutes at the sink to ensure that the conc at the sink is always lower than at the source

52
Q

mass flow

A

(At source) sucrose is actively
(transported) into the phloem/sieve
element/tube;
2. By companion/transfer cells;
3. Lowers water potential in
phloem/sieve element/tube and
water enters by osmosis;
4. (Produces) high (hydrostatic)
pressure;
5. Mass flow/transport towards
sink/roots/storage tissue;
6. At sink/roots sugars are
removed/unloaded;

53
Q

ringing experiment

A

-a ring of bark which contains phloem is removed from a tree trunk
-this causes the trunk to swell above the removed section
-the liquid in this swelling contains a high conc of sugars whereas the fluid below the ring has a much lower conc.
-this shows that when the phloem is removed, sugars can’t be transported so the phloem must transports sugars

54
Q

radioactive tracers

A

-provide one part of the plant with only radioactively labelled carbon dioxide containing 14C
-after some time, cut sections from the stem and use audiography by placing the cut section on photographic film. If the film turns black, the radioactive 14C isotope is present
-this shows that sugars are transported around the plant via translocation in the phloem