Topic 28 (subtopic): Amides

Question 1

Amide functional group

Answer 1

− CONR2 carbonyl group attached to amine group

Question 2

Boiling point of amides

Answer 2

Decrease as * increases
primary amides have 2 H atoms to H bond with, tertiary can’t H bond (with itself)

Question 3

Nomenclature of amides

Answer 3

Remove oic acid and add amide (one word not two)
dont forget N if substituent on N

Question 4

Making amides

Answer 4

Acyl chloride (ethanoyl chloride) and ammonia

Question 5

Making amides equation ammonia

Answer 5

CH3COCl + NH3 —> CH3CONH2 + HCl(g)

Question 6

.

Question 7

Amide and acidic solution (acid hydrolysis)

Answer 7

CH3CONH2 + H2O + HCl —> CH3COOH + NH4Cl (ammonium salt)

Question 8

Amide and alkaline solution

Answer 8

CH3CONH2 + NaOH —> CH3COONa + NH3

Question 9

Identification of Amides

Answer 9

Warm with dilute NaOH solution and test for NH3 production using moist red litmus paper which turns blue

Question 10

Reduction of amides

Answer 10

CH3CONH2 + 4[H] —> CH3CH2NH2 + H2O

Question 11

Amide H bonding

Answer 11

All form H bonds with water

Question 12

Amide solubility

Answer 12

Shorter chains soluble in water

Question 13

Making amides ammonia reagent

Answer 13

Ammonia

Question 14

Making amides conditions ammonia

Answer 14

Low temp, excess ammonia

Question 15

Making amides mechanism name

Answer 15

Addition elimination

Question 16

Making amides (amines) equation

Answer 16

CH3COCl +C2H5NH2 —> CH3CONHC2H5 + HCl(g)
N substituted amine

Question 17

Making amides conditions amines

Answer 17

Anhydrous