Topic 28: Amines

Question 1

Amine functional group

Answer 1

R-NH2

Question 2

Naming amines

Answer 2

Methylamine CH3NH2
Ethylmethylamine (C2H5)(CH3)NH

Question 3

Making an amine using haloalkane

Answer 3

Nucleophilic substitution of haloalkane with :NH3 creates primary amine

Question 4

Only make primary amine

Answer 4

Excess ammonia otherwise the amine can act as the nucleophile with the haloalkane to make a secondary alkane.

Question 5

Quaternary amine use

Answer 5

Cationic surfactant, used in hair conditioner

Question 6

Making an amine from nitrile

Answer 6

Reduction of nitriles
Reducing agent [H]
CH3CH2CN + 4[H] —> CH3CH2CH2NH2

Question 7

Reducing agent for making amine from nitrile

Answer 7

LiAlH4 in ether
or
2H2 with Ni catalyst

Question 8

Amines as bases

Answer 8

Increases in “goodness” of base as lone pair becomes more available.
Most available in primary amine then ammonia then phenylamine

Question 9

Inductive effect

Answer 9

Electron pushing effect

Question 10

Making phenylamine

Answer 10

Nitrobenzene is reduced to phenyl benzene

Question 11

Conditions for making phenylamine

Answer 11

Tin catalyst, conc. HCl, under reflux makes

Question 12

Intermediate of making phenylamine

Answer 12

Phenylammonium salt then react with NaOH