Topic 21: Measurement and Analysis (HL)

Question 1

Tetramethylsilane, TMS

Answer 1

Standard reference in H NMR.

Question 2

Why is TMS used as the standard reference in H NMR?

Answer 2

1) 12 protons are in the same chemical environment, so there’ll be one single, strong peak
2) inert
3) absorbs upfield
4) easily removed from the sample after measurement - volatile.