topic 2 cells and control Flashcards

1
Q

What is the cell cycle?

A
  • A series of events that take place in a cell involving cell growth, DNA replication cell division
  • It is described as the lifecycle of a cell
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2
Q

state the three stages of the cell cycle

A

stage 1 - interphase
stage 2- mitosis
stage 3 - cytokinesis

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3
Q

what is interphase?

A

the longest stage of the cell cycle that involves cell growth, the synthesis of the new organelles and DNA replication replication

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4
Q

what does DNA replication involve?

A
  • double helix unzips exposing two strands
  • DNA bases align next to complementary bases on the DNA strands
  • complementary base pairs join
  • two identical DNA molecules formed
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5
Q

what is a chromosome?

A

A linear DNA molecule tightly coiled around proteins

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6
Q

what happens to chromosomes during DNA replication?

A

The DNA in the ‘arm’ of each chromosome (chromatid) is replicated.

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7
Q

What is mitosis?

A

A form of cell division that produces two diploid ‘daughter’ cells, both genetically identical to the parent cell.

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8
Q

Why is mitosis important?

A

asexual reproduction, growth, repair of damaged cells, cell replacement

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9
Q

State the four stages of mitosis

A

prophase, metaphase, anaphase, telophase

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10
Q

Outline Prophase

A
  • DNA condenses, chromosomes become visible

- Nuclear membrane disappears

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11
Q

outline metaphase

A

chromosomes line up along cell equator

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12
Q

outline anaphase

A

spindle fibres attach to each chromosome and arms of each chromosome pulled to opposite poles, chromatids separated

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13
Q

Outline Telophase

A

● Nucleus of the cell divides

● New membrane forms around each set of chromosomes

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14
Q

what does cytokinesis involve?

A

● Division of the cell membrane and cytoplasm

● Two genetically identical ‘daughter’ cells produced

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15
Q

what is cancer

A

uncontrolled cell division results in formation of a tumour (mass of cells)

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16
Q

What does the 95th percentile mean?

A

What does the 95th percentile mean?

17
Q

what are percentile charts?

A

● A chart used to monitor growth

● Measurements (e.g. fetal length or head circumference) can be compared to the expected values at a certain age

18
Q

What can doctors determine from percentile charts?

A

● Slower growth than normal (below the bottom line)
● Faster growth than normal (above the top line)
● Abnormal growth (irregular growth patterns)

19
Q

describe growth in animals?

A

● Cell division occurs in all body cells. It occurs at a slower rate in adults than in younger animals as growth stops and cell division is only required for replacement and repair.
● Most cells differentiate at an early stage and become specialised. Some adult stem cells retain their ability to differentiate.

20
Q

describe growth in plants?

A

● Cell division can only occur in meristematic tissue. The rate of cell division remains the same throughout a plant’s life.
● Meristematic stem cells can differentiate into any cell type for as long as the plant lives
● Cell elongation occurs in all cells. Cells expand and enlarge enabling growth of the plant.

21
Q

What are stem cells?

A

unspecialized cells from which differentiated cells develop

22
Q

what is meant by differentiation

A

● The process by which stem cells become specialised (have a specific function)

23
Q

Why is cell differentiation important?

A

Enables the formation of specialised tissues with specific functions e.g. muscle tissue

24
Q

What are embryonic stem cells?

A

Stem cells found in very early embryos that are unspecialised and capable of differentiating into any cell type

25
what is the function of embryonic stem cells?
enable the growth and development of tissues in human embryos
26
What are adult stem cells?
Stem cells that can differentiate into a limited range of cell types e.g. bone marrow stem cells
27
what is the primary function of adult stem cells?
replacement of dead cells
28
Where are stem cells found in plants?
meristems
29
Where is meristem tissue found?
In regions of the plant where cells are continuously dividing e.g. root tips, shoot tips
30
what are meristematic stem cells?
Stem cells found in meristems that are unspecialised and capable of differentiating into any cell type during the life of a plant
31
How can stem cells be used in medicine?
● Stem cells collected ● Stem cells stimulated to differentiate into specific cell types e.g. heart muscle cells ● Specialised cells transplanted into the patient ● Used to treat damage or disease e.g. heart disease
32
Where can embryonic stem cells be collected from?
● Donor stem cells removed from embryos grown in vitro | ● Patient's own stem cells removed from the umbilical blood before birth
33
what are the benefits of using stem cells in medicine?
● Treat damage or disease e.g. heart disease, type 1 diabetes ● Treat diseases that would otherwise be untreatable ● Used in scientific research ● Growing organs for transplants
34
what are the risks of stem cell use in medicine
● Transplanted stem cells could cause tumours ● Finding suitable stem cell donors is a difficult task ● Stem cells may be rejected by the body (immunosuppressants taken) ● Potential side effects ● Long term risks of using stem cells unknown ● Stem cells may become contaminated during preparation and when transplanted transmit infections to the patient, making them sicker
35
what are the ethical issues related to the use of stem cells?
the embryos that were used to provide stem cells are destroyed which is seen as unethical