Topic 2 - Amino Acids Flashcards
Non Polar
Glycine/Gly/G
Alanine/Ala/A
Valine/Val/V
Leucine/Leu/L
Isoleucine/Ile/I
Methionine/Met/M
Proline/Pro/P
(GAVLIMP)
Aromatic
Phenylalanine/Phe/F
Tryptophan/Trp/W
Tyrosine/Tyr/Y (pKa = 10)
(PTT/FWY)
Polar, Uncharged
Cysteine/Cys/C (pKa = 8.5)
Serine/Ser/S (pKa = 13)
Threonine/Thr/T (pKa = 13)
Asparagine/Asn/N
Glutamine/Gln/Q
(CSTAG/CSTNQ)
Polar, Positively Charged (Basic)
Histidine/His/H (pKa = 6)
Arginine/Arg/R (pKa = 12.5)
Lysine/Lys/K (pKa = 10.5)
(HAL/HRK)
Polar, Negatively Charged (Acidic)
Aspartic Acid/Aspartate/Asp/D (pKa = 4)
Glutamic Acid/Glutamate/Glu/E (pKa = 4)
(DE)
Glycine
Glycine
Gly
G
(Non Polar)
Alanine
Alanine
Ala
A
(Non Polar)
Valine
Valine
Val
V
(Non Polar)
Leucine
Leucine
Leu
L
(Non Polar)
Isoleucine
Isoleucine
Ile
I
(Non Polar)
Methionine
Methionine
Met
M
(Non Polar)
Proline
Proline
Pro
P
(Non Polar)
Phenylalanine
Phenylalanine
Phe
F
(Aromatic)
Tryptophan
Tryptophan
Trp
W
(Aromatic)
Tyrosine
Tyrosine
Tyr
Y
(Aromatic)
pKa = 10
Serine
Serine
Ser
S
(Polar, Uncharged = OH)
pKa = 13
Threonine
Threonine
Thr
T
(Polar, Uncharged = OH)
pKa = 13
Asparagine
Asparagine
Asn
N
(Polar, Uncharged = NH2)
Glutamine
Glutamine
Gln
Q
(Polar, Uncharged = NH2)
Histidine
Histidine
His
H
(Polar, Charged = NH+)
pKa = 6
Arginine
Arginine
Arg
R
(Polar, Charged = NH2+)
pKa = 12.5
Lysine
Lysine
Lys
K
(Polar, Charged = NH3+)
pKa = 10.5
Aspartic Acid
Aspartic Acid
Asp
D
(Polar, Charged = COO-)
pKa = 4
Glutamic Acid
Glutamic Acid
Glu
E
(Polar, Charged = COO-)
pKa = 4
a-Carboxyl of free amino acid
a-Carboxyl of free amino acid
-COOH
pKa = 2
C-terminal carboxyl
C-terminal carboxyl
-COOH
pKa = 3
N-terminal amino group
N-terminal amino group
-NH3
pKa = 8
a-Amino of free amino acid
a-Amino of free amino acid
-NH3
pKa = 9.5
