Topic 2 Flashcards
DNA
CHOPN
Protein
CHOSN
Water is a ….
Polar molecule due to highly electronegative oxygen atom
Dipole
Unequal distribution of e-
(cohesion) H2O can interact with any
polar or charged molecule
(strong) Covalent bonds
is the sharing of a pair of valence electrons by two atoms. Molecules consist of 2+ atoms with covalent bonds
(strong) Ionic bonds
e- is transferred between two atoms with opposite electronegativities, atoms become charged and stay associated
(weak) hydrogen bond
forms when a hydrogen atom covalently bound to an electronegative atom is also attracted to another electronegative atom
(weak) Vander Waal
interactions are attractions between molecules that are close together as a result of these charges
Why are carbons good?
- Can bond with 4 other atoms
- Can form chains
- Can form abundant (molecular diversity)
Macromolecules
are large and complex molecules that are composed of many covalently connected atoms
Polymer
is a long molecule consisting of many similar building blocks
monomers
The smaller, repeating molecules that serve as building blocks
4 of lifes organic molecules are polymers
Carbohydrates, Proteins, Nucleic acids, and Lipids
Synthesis
Growing the chain
requires energy
Breakdown
Cleavage of covalent
energy is available
Carbohydrates
include sugar and polymers of sugars .
Energy storage.
Cell structure.
Cell-cell recognition
Simple or single sugars
monosaccharides (CH2O)
Carbohydrate macromolecules
polysaccharide
Glucose (C6 H12 O6)
the main energy source for cells
disaccharide
forms when a dehydration reaction joins two monosaccharides.
Glycosidic linkage
starch
a storage polysaccharides of plants, consists entirely of glucose monomers.
Surplus starch
store as granules within chloroplasts, and other plastids
Glycogen
storage polysaccharide in animals and fungi (mainly in liver and muscle cells.
Hydrolysis of glycogen
releases glucose when the demand for energy increases.
Cellulose
major component of plants cell walls
polymer of glucose
chitin (polysaccharide)
is found in arthropod exoskeletons and fungal cell walls
lipids
are the one class of large biological molecules that does not form polymers
fats
storage of energy
glycerol and fatty and acid
phospholipids
membranes
steroids
membranes, hormones signalling
Glycerol
3C alcohol, each C has an OH (reactive
Fatty acids
a long CH chain carboxyl (O=C-HO) group at one end
Saturated fats
Only C-C
Most animal fat
Unsaturated fats
Some C=C liquid
Steroids
CH skeleton with 4 rings fused
Hormones: estrogen, testosterone , Cholesterol
Stability of membranes
Functions of protein
Catalyzing chemical reactions Structural support Storage Transport Cellular communications Movement Defense against foreign substances
amino acids are linked by
peptide
Primary structure
is determined by inherited genetic information
Secondary structure
interaction b/w backbone polypeptide
helix, sheet
Tertiary Structure
Overall shape of polypeptide and is determined by interactions between R groups, not by interactions between constituents
Quaternary structure
results when two or more polypeptide chains form one macromolecule
Affect protein structure
pH
Salt concentration
Temperature
other environmental
Nucleic acids
Provides directions for its own replication
Directs synthesis of messenger RNA ((mRNA and through mRNA controls protein systhesis (gene expression - ribosomes)
RNA
transmit info in the cell
miRNA
gene regulation
snRNA
splicing
Components of nucleic acids
1’C - Nitro base attaches
2’C - DNA just H RNA OH
3’C - essential for polymerization
5’C- Phosphate group attaches
Basic structure of monomer
1) nitrogen base
2) 5C sugar (pentose)
3) Phosphate group
nucleoside
nitrogenous + sugar
nucleotide
nucleoside + phosphate group
Pyrimidines
single ring
Cytosine
Thymine
Uracil
Purines
double ring
Adenine
Guanine
DNA
H
RNA
OH
Backbone
suagr phosphate
Phosphodiester
Covalent dehydration reaction