Topic 19 (A) Flashcards
•More 5-HT releasing properties
•Re-inforcing due to dopamine effects
•Increased energy
•Enhanced sensory perceptions
•Altered concept of time
•Increased Heart Rate
•Dry mouth
•At high doses:
Hallucinations
Agitation
Panic attacks
MDMA (Ecstasy)
Coined by Humphrey Osmond (1956)
“Manifesting the soul/mind”
Psychedelic
Use of psychedelics as part of indigenous religions/spiritual practices
Ethneogenic
•Activated multiple 5HT receptors
•5HT2a particularly associated with hallucinations and altered perceptions
•Increase neuroplasticity
• allows new connections in the brain to be made
Pharmacology of LSD
Phase ll clinical trials for treatment resistant depression
LSD/psilocybin
Phase lll clinical trial for PTSD
MDMA
Assessing mental & physical suitability- Therapeutics (LSD & MDMA)
Stage 1 - Assesment
Trained therapist provides info on expectations and navigating the experience
Therapeutics (MDMA & LSD)
Stage 2 - preparation
Receive drug in controlled setting with train therapist present
Therapeutics (MDMA & LSD)
Stage 3 - Experience session
Post treatment discussion with therapist of how treatment experience relates to the illness
Therapeutics (MDMA & LSD)
Stage 4 - integration session