Topic 1 The Cell Cycle Flashcards
Genome
The entire genetic information of an organism.
Chromosome
A package of DNA, named after the stained appearance they produce when dyed.
Sister Chromatids
Duplicated DNA that is attached at the Centromere to its identical strand.
Centromere
The location at which sister chromatids are attached by a protein called cohesin.
Interphase
The longest part the cell cycle in which the cells prepares the mitosis. The phase contains three distinct sub-phases: G1,S,G2.
Prophase
Part of the mitotic phase, the prophase consists of:
- Chromatin condenses into chromosomes.
- Nucleoli disappears.
- Mitotic Spindle Begins to Form.
- Centrosomes begin to move away from one another.
Prometaphase
Part of the Mitotic cycle, prometaphase consists of:
- Nuclear envelope fragments
- Kinetochores attach to both sister chromatids at the centrosomes.
- Some microtubules attach to Kinetochores to form kinetochore microtubules.
- Nonkinetochore Microtubules interact with other from the opposite pole of the spindle.
- Chromosomes have become more condensed.
- Microtubules begin to invade the nuclear area.
Metaphase
Part of the Mitotic phase in which:
- Centrosomes are situated at both poles of the cell.
- Chromosomes are aligned along the metaphase plate.
- All chromosomes are attached to microtubules.
Anaphase
Part of the Mitotic cycle in which:
-Cohesin is cleaved.
-Chromatids move towards the poles of the cell.
The cell elongates as the non-kinetochore microtubules push against each other.
Telophase
Part of the Mitotic cycle in which:
- The chromosomes become less condensed.
- Microtubules become de polymerized.
- Nuclei form in both daughter cells.
- Nucleoli reappear
- Mitosis Complete
Cytokinesis
A splitting of cells that have undergone Mitosis to form two daughter cells.
Cleavage Furrow
The process of pinching off two daughter cells during cytokinesis. Can be seen as an indentation of the cell wall surface.
Mitosis
The process in which somatic cells divide to produce two identical daughter cells that contain the same type and same number of chromosomes.
Mitotic Spindle
A structure consisting of fibers made of microtubules and proteins.
Microtubules
Positions chromosomes during mitosis.